{"id":"W3130524456","doi":"10.1016/j.jacbts.2020.11.013","title":"Acute Kidney Injury Results in Long-Term Diastolic Dysfunction That Is Prevented by Histone Deacetylase Inhibition","year":2021,"lang":"en","type":"article","venue":"JACC Basic to Translational Science","topic":"Acute Kidney Injury Research","field":"Medicine","cited_by":32,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Institutes of Health; American Heart Association; Canadian Institutes of Health Research; U.S. Department of Veterans Affairs","keywords":"Medicine; Acute kidney injury; Metabolome; Histone deacetylase; Diastole; Cardiology; Internal medicine; Renal function; Fibrosis; Kidney; Cardiac fibrosis; Kidney disease; Cardiac dysfunction; Histone deacetylase inhibitor; Heart failure; Histone; Blood pressure; Biology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002997835,0.0005115055,0.0007038487,0.0003176711,0.0002021443,0.0003694968,0.0003040229,0.0003078819,0.0009972792],"category_scores_gemma":[0.000189426,0.0001865818,0.000606061,0.000203872,0.0002943186,0.0003070157,0.0001915359,0.001139333,0.0002544044],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001980066,"about_ca_system_score_gemma":0.000298758,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004128331,"about_ca_topic_score_gemma":0.00122493,"domain_scores_codex":[0.9998258,0.00002022443,0.00002048525,0.00002954476,0.00003944167,0.00006456492],"domain_scores_gemma":[0.9997129,0.00001321082,0.0001121671,0.0000266476,0.00002459098,0.0001105416],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002774305,0.0006559416,0.001562999,0.000152813,0.0001042616,0.0001140976,0.00003412076,0.00009498303,0.9828669,0.000156418,0.0003304739,0.01115259],"study_design_scores_gemma":[0.0005066412,0.01353238,0.05638126,0.00004486003,0.0002395326,0.0007850077,0.000141467,0.00095413,0.9226618,0.0002509054,0.004469475,0.00003251207],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.993301,0.002936774,0.001998403,0.0002905865,0.0001363065,0.00003036185,0.0003022074,0.000164219,0.0008401719],"genre_scores_gemma":[0.9946758,0.001916166,0.001091315,0.0001341659,0.0000471301,0.00003692904,0.0004536685,0.00001833554,0.00162654],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009972792,"threshold_uncertainty_score":0.003336191,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02446937754281498,"score_gpt":0.3472060605553407,"score_spread":0.3227366830125257,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}