{"id":"W3130836962","doi":"10.1016/j.heliyon.2021.e06180","title":"α-Glucosidase inhibitory activity of compounds isolated from the twig and leaf extracts of Desmos dumosus","year":2021,"lang":"en","type":"article","venue":"Heliyon","topic":"Traditional and Medicinal Uses of Annonaceae","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Thailand Science Research and Innovation","keywords":"Acarbose; Absolute configuration; Circular dichroism; Enantiomer; Chemistry; Twig; Stereochemistry; IC50; Organic chemistry; In vitro; Enzyme; Botany; Biochemistry; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006333516,0.00007826027,0.0001214418,0.000009145947,0.00003529647,0.000004325042,0.00006049973,0.00007898728,0.00001617041],"category_scores_gemma":[0.00005585128,0.00006009441,0.00004986024,0.00004530207,0.0001353158,0.000003846661,0.00004982862,0.00007883449,0.00000115623],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000004015494,"about_ca_system_score_gemma":0.00008277047,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004656637,"about_ca_topic_score_gemma":0.00005615717,"domain_scores_codex":[0.9994744,0.00004995596,0.0001236305,0.0001586109,0.0001060558,0.00008732671],"domain_scores_gemma":[0.9995471,0.00005848531,0.00007535505,0.0001722744,0.0001000994,0.00004667544],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001977191,0.0001145343,0.001871368,0.00005845702,0.00004562695,0.000009297269,0.00005455337,0.000003038649,0.9955925,0.00003463479,0.000779859,0.001238465],"study_design_scores_gemma":[0.0005259756,0.0002174633,0.08008946,0.0001359918,0.00002993508,0.00002683875,0.00008955117,0.000006760418,0.9093094,0.00005858856,0.009439168,0.00007080093],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9901873,0.008655701,0.0001015343,0.0004134881,0.00009742042,0.00005156016,0.00008542794,0.00000339901,0.0004042078],"genre_scores_gemma":[0.9978297,0.001398462,0.0001219521,0.0002306553,0.0001480437,0.000002319197,0.0001211685,0.000006821362,0.0001409244],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.08628298,"threshold_uncertainty_score":0.2450579,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01372879126934845,"score_gpt":0.2356215074740281,"score_spread":0.2218927162046796,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}