{"id":"W3130979972","doi":"10.3390/cancers13040781","title":"Prognostic Significance of CD4+ and CD8+ Tumor-Infiltrating Lymphocytes in Head and Neck Squamous Cell Carcinoma: A Meta-Analysis","year":2021,"lang":"en","type":"review","venue":"Cancers","topic":"Cancer Immunotherapy and Biomarkers","field":"Medicine","cited_by":125,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Cancer Research UK","keywords":"Head and neck squamous-cell carcinoma; Head and neck; Basal cell; Medicine; Tumor-infiltrating lymphocytes; CD8; Pathology; Meta-analysis; Oncology; Internal medicine; Cancer research; Head and neck cancer; Immunology; Immune system; Cancer; Surgery","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003502956,0.0004933891,0.004517113,0.0004024377,0.00004857553,0.00003557887,0.0001171083,0.0001783649,0.0001566746],"category_scores_gemma":[0.00009954866,0.0003859149,0.001247074,0.00146259,0.0002372727,0.00005173639,0.00004587182,0.0002710604,5.784495e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001014747,"about_ca_system_score_gemma":0.002854998,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003673633,"about_ca_topic_score_gemma":0.0007410588,"domain_scores_codex":[0.9975094,0.0001943717,0.0009535622,0.0007255877,0.000273066,0.0003440313],"domain_scores_gemma":[0.9982717,0.0004600358,0.0005907234,0.0004492795,0.00009118082,0.0001370763],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.001120783,0.0003514331,0.02313608,0.2353539,0.1433442,0.001771885,0.002774357,0.0001394933,0.000582956,0.00003635154,0.0008886127,0.5904999],"study_design_scores_gemma":[0.005916181,0.001044665,0.00208413,0.006538968,0.7260354,0.0003637619,0.0009884895,0.0002084468,0.0004993956,0.000005613217,0.2546975,0.001617535],"study_design_candidate":"meta_analysis","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.01202057,0.9862568,0.000005287548,0.00002382143,0.00006331653,0.001151649,0.0001272507,0.00001456024,0.0003367893],"genre_scores_gemma":[0.0929129,0.9058703,0.0003403017,0.0001205762,0.00005394085,0.0003533143,0.00007924441,0.00004843795,0.0002209477],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.5888824,"threshold_uncertainty_score":0.9998593,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07082424784178697,"score_gpt":0.3268750311253219,"score_spread":0.2560507832835349,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}