{"id":"W3131001021","doi":"10.1042/bst20200694","title":"It's not just a phase; ubiquitination in cytosolic protein quality control","year":2021,"lang":"en","type":"review","venue":"Biochemical Society Transactions","topic":"Ubiquitin and proteasome pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canada's Michael Smith Genome Sciences Centre; University of British Columbia","funders":"Canadian Institutes of Health Research","keywords":"Ubiquitin; Proteostasis; Cell biology; Proteasome; Cytosol; Deubiquitinating enzyme; Biology; Endoplasmic-reticulum-associated protein degradation; F-box protein; Protein folding; Ubiquitin ligase; Biochemistry; Enzyme","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0005234698,0.0005244868,0.00116019,0.00004454923,0.0001479827,0.0000587027,0.0003217601,0.001297846,0.0001891133],"category_scores_gemma":[0.0001179882,0.0005268381,0.001700363,0.0003873188,0.0001596944,0.000007301941,0.00002846996,0.0007345612,0.00001987085],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001530358,"about_ca_system_score_gemma":0.0005883937,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002773361,"about_ca_topic_score_gemma":0.00001378227,"domain_scores_codex":[0.9970479,0.0003717913,0.0008994922,0.0008872137,0.0002881833,0.0005054084],"domain_scores_gemma":[0.9988121,0.00007549331,0.0002735311,0.0005260215,0.0001302876,0.0001825276],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001072648,0.002425253,7.919363e-7,0.01653595,0.001160739,0.00001087748,0.000494019,0.000004248419,0.4285967,0.0001330438,0.005962434,0.5445687],"study_design_scores_gemma":[0.001619117,0.0001047274,4.268975e-7,0.002071982,0.0003055772,0.00001904004,0.0001041165,0.00001383105,0.07697169,0.000004509455,0.9181577,0.0006272668],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0005285452,0.9781158,0.01747992,0.0005259067,0.0001350185,0.001712437,0.001173715,0.0000488382,0.0002798336],"genre_scores_gemma":[0.009824455,0.9839202,0.0009314385,0.0006386391,0.0004471606,0.001551421,0.002011817,0.00008593235,0.0005889079],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9121953,"threshold_uncertainty_score":0.9999987,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06683088815001548,"score_gpt":0.3739189777819114,"score_spread":0.3070880896318959,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}