{"id":"W3131069104","doi":"10.22541/au.161256029.96919985/v1","title":"IL-13 signature in severe adult asthmatics with airway neutrophilia: a new endotype to treat!","year":2021,"lang":"en","type":"preprint","venue":"","topic":"Asthma and respiratory diseases","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"McMaster University; St. Joseph’s Healthcare Hamilton","funders":"Canadian Institutes of Health Research; GlaxoSmithKline; AstraZeneca","keywords":"Neutrophilia; Endotype; Airway; Medicine; Signature (topology); Asthma; Internal medicine; Surgery; Mathematics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003930844,0.0003291813,0.0006418665,0.0002303744,0.0001552184,0.0006758222,0.000192035,0.0004870191,0.003081267],"category_scores_gemma":[0.0005633319,0.0001129608,0.0004045121,0.0002282345,0.0002290398,0.0003862863,0.0004019834,0.0008908797,0.0007747395],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001913649,"about_ca_system_score_gemma":0.0004550564,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003243941,"about_ca_topic_score_gemma":0.0006449896,"domain_scores_codex":[0.9998511,0.00004106794,0.0000148576,0.00002123448,0.00003929395,0.00003229213],"domain_scores_gemma":[0.9998253,0.00003369851,0.000036194,0.00001683068,0.00004359057,0.00004431348],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.01277161,0.0004205529,0.2279054,0.001690805,0.0006130522,0.005414051,0.0003691666,0.001659384,0.1476889,0.003826198,0.06337395,0.5342669],"study_design_scores_gemma":[0.00117822,0.002662029,0.7761462,0.001588662,0.001291782,0.01414313,0.001538824,0.01075435,0.04140383,0.01422803,0.1349327,0.0001322301],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8612162,0.07292295,0.01511843,0.03045059,0.004051893,0.0002178907,0.004388896,0.0005734122,0.01105972],"genre_scores_gemma":[0.9456141,0.02074456,0.01257168,0.0051768,0.00325224,0.0001747257,0.002863445,0.0001262098,0.009476149],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003081267,"threshold_uncertainty_score":0.01030785,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009414683215746534,"score_gpt":0.2480374146083754,"score_spread":0.2386227313926289,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}