{"id":"W3131163518","doi":"10.3390/ijms22042205","title":"Rainbow Trout (Oncorhynchus mykiss) Na+/H+ Exchangers tNhe3a and tNhe3b Display Unique Inhibitory Profiles Dissimilar from Mammalian NHE Isoforms","year":2021,"lang":"en","type":"article","venue":"International Journal of Molecular Sciences","topic":"Physiological and biochemical adaptations","field":"Environmental Science","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Amiloride; Trout; Intracellular pH; Gene isoform; Rainbow trout; Osmoregulation; Chemistry; Sodium; Biology; DAPI; Biochemistry; Intracellular; Fish <Actinopterygii>; Ecology; Fishery","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008354367,0.0001823324,0.0001871901,0.0001080988,0.000134839,0.0002105712,0.00009761165,0.0001822376,0.0009823261],"category_scores_gemma":[0.00006413543,0.0001021581,0.0002970466,0.0000955607,0.0001489842,0.0001711208,0.0001924199,0.000316013,0.0001855358],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001979428,"about_ca_system_score_gemma":0.0002057659,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002359684,"about_ca_topic_score_gemma":0.005972011,"domain_scores_codex":[0.9999343,0.000003626406,0.00000776533,0.00001821258,0.00001988613,0.00001619472],"domain_scores_gemma":[0.9999536,0.000004626521,0.00001372449,0.000003708194,0.000008963093,0.00001538042],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003582797,0.000004720921,0.0005589247,0.00001206178,0.000002728752,0.00001452077,0.000004987005,0.000009909561,0.9990016,0.00001662746,0.00001110092,0.0003270405],"study_design_scores_gemma":[0.00004345004,0.0006238965,0.1800206,0.000009310346,0.00004834395,0.0007692205,0.0001226234,0.0008704912,0.8136875,0.00008414916,0.003706685,0.00001368275],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9973509,0.0005781525,0.0009922897,0.00005132864,0.00001058257,0.00001186504,0.0002649364,0.00002804957,0.0007119925],"genre_scores_gemma":[0.9933735,0.0006482576,0.00222983,0.00008442228,0.000007928791,0.00002692083,0.0008048071,0.00001238251,0.00281195],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002359684,"threshold_uncertainty_score":0.004691899,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01333307661470084,"score_gpt":0.2496253880632533,"score_spread":0.2362923114485525,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}