{"id":"W3131314974","doi":"10.1039/d0lc01194k","title":"Investigations on T cell transmigration in a human skin-on-chip (SoC) model","year":2021,"lang":"en","type":"article","venue":"Lab on a Chip","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":56,"is_retracted":false,"has_abstract":true,"ca_institutions":"Victoria General Hospital; University of Winnipeg; University of Manitoba","funders":"National Eye Institute; Air Force Office of Scientific Research; Defense Advanced Research Projects Agency; Multidisciplinary University Research Initiative; University of Manitoba; National Institutes of Health; National Institute of Allergy and Infectious Diseases; Natural Sciences and Engineering Research Council of Canada; National Psoriasis Foundation","keywords":"Human skin; Chip; Drug; Computer science; Pharmacology; Medicine; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00013516,0.0002464674,0.0002918443,0.0001908753,0.0002484325,0.0000198407,0.0001980454,0.0003936343,0.0003820452],"category_scores_gemma":[0.00003660577,0.0002301049,0.0001160886,0.0002422936,0.0001596103,0.00004944577,0.00002933057,0.0007244531,0.0009550838],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005925281,"about_ca_system_score_gemma":0.0001107437,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009249977,"about_ca_topic_score_gemma":0.0005846444,"domain_scores_codex":[0.9984379,0.0003252328,0.0003345117,0.0004690379,0.00004877107,0.000384592],"domain_scores_gemma":[0.999268,0.0001405324,0.00008568086,0.0004368854,0.00003902059,0.00002991276],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001020858,0.0008199609,0.000258909,0.00001605035,0.00003366414,0.00001557018,0.001520032,0.0008367658,0.9649971,0.02886953,0.001979666,0.0005506223],"study_design_scores_gemma":[0.002751093,0.0005198171,0.001390157,0.00007052355,0.00002537224,0.00001343412,0.0001823716,0.0001678151,0.9794907,0.007060525,0.008027134,0.0003010575],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9745908,0.0003564519,0.000081522,0.001530613,0.000304034,0.0002103579,0.00003464987,0.00008594493,0.02280567],"genre_scores_gemma":[0.9816858,0.00005252064,0.00008924206,0.002464714,0.0000320739,0.00004959498,0.0003924995,0.00002664598,0.0152069],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02180901,"threshold_uncertainty_score":0.9998228,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02058382538914262,"score_gpt":0.2353335366285431,"score_spread":0.2147497112394005,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}