{"id":"W3131331017","doi":"10.3762/bjoc.17.40","title":"Biochemistry of fluoroprolines: the prospect of making fluorine a bioelement","year":2021,"lang":"en","type":"review","venue":"Beilstein Journal of Organic Chemistry","topic":"Fluorine in Organic Chemistry","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":39,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs","keywords":"Chemistry; Amino acid; Context (archaeology); Proline; Folding (DSP implementation); Protein engineering; Proteome; Computational biology; Biochemistry; Protein folding; Enzyme; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003058474,0.0004829482,0.0004871988,0.000911914,0.0002123858,0.0004958764,0.0004019429,0.0008808441,0.00124654],"category_scores_gemma":[0.0002552229,0.0002072735,0.0002929689,0.0006256179,0.0004658894,0.0009900918,0.0003564949,0.001378801,0.0009098033],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005604065,"about_ca_system_score_gemma":0.00045617,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007014197,"about_ca_topic_score_gemma":0.0009105813,"domain_scores_codex":[0.9998885,0.00002160279,0.000009209492,0.00002313882,0.00004099512,0.00001647457],"domain_scores_gemma":[0.9999171,0.00003958504,0.00001068816,0.000005184258,0.00001897229,0.000008359954],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001551021,0.0001357286,0.0003004889,0.01196127,0.00007380138,0.0004807826,0.0001504492,0.001655785,0.06731229,0.03311303,0.01382182,0.8708395],"study_design_scores_gemma":[0.00001262162,0.0001867899,0.0004599642,0.0006302932,0.00004404576,0.001288807,0.00003210389,0.0003000155,0.02153544,0.003739357,0.9717486,0.00002195045],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001441039,0.993378,0.00137444,0.0003898069,0.0002490606,0.000005415309,0.00002283564,0.00001782156,0.003121566],"genre_scores_gemma":[0.01402065,0.980857,0.001633938,0.0003143846,0.0002398574,0.00001468491,0.00005100347,0.000006325834,0.002862026],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.00124654,"threshold_uncertainty_score":0.00417012,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1198684222873392,"score_gpt":0.4578047502645782,"score_spread":0.337936327977239,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}