{"id":"W3131780647","doi":"10.2967/jnumed.120.259069","title":"Prospective, Single-Arm Trial Evaluating Changes in Uptake Patterns on Prostate-Specific Membrane Antigen–Targeted <sup>18</sup>F-DCFPyL PET/CT in Patients with Castration-Resistant Prostate Cancer Starting Abiraterone or Enzalutamide","year":2021,"lang":"en","type":"article","venue":"Journal of Nuclear Medicine","topic":"Prostate Cancer Treatment and Research","field":"Medicine","cited_by":52,"is_retracted":false,"has_abstract":true,"ca_institutions":"Sunnybrook Health Science Centre; McMaster University; University of British Columbia","funders":"","keywords":"Medicine; Prostate cancer; Enzalutamide; Glutamate carboxypeptidase II; Nuclear medicine; Urology; Prospective cohort study; Prostate-specific antigen; Clinical trial; Internal medicine; Oncology; Cancer; Androgen receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002780969,0.001395206,0.001644171,0.0003062589,0.0003953475,0.0008952816,0.0005594494,0.001076041,0.002126901],"category_scores_gemma":[0.001573415,0.0006043084,0.001000713,0.0003911594,0.0008400381,0.0006785871,0.0003179932,0.001867054,0.0005230425],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006227162,"about_ca_system_score_gemma":0.001386301,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007933816,"about_ca_topic_score_gemma":0.001759329,"domain_scores_codex":[0.9992318,0.0004779827,0.00004295199,0.000114209,0.00004678304,0.00008621936],"domain_scores_gemma":[0.9985299,0.0003094314,0.0003772648,0.0001837485,0.0001135628,0.000486077],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.9304129,0.01638336,0.01195438,0.000176737,0.0006231814,0.0001044293,0.0001197914,0.001087716,0.01844321,0.00006755412,0.0004954007,0.02013124],"study_design_scores_gemma":[0.440474,0.5271,0.0260093,0.00002117941,0.0004901755,0.0001831643,0.00006093277,0.001187641,0.003485789,0.0001158506,0.0008412985,0.00003052427],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9968805,0.0007808639,0.0002785807,0.0001044824,0.0000415384,0.001032355,0.0003289327,0.00003270068,0.000520013],"genre_scores_gemma":[0.9955767,0.0003573487,0.00118233,0.0002475865,0.00009992757,0.001152998,0.0007729279,0.00001421198,0.000595895],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002780969,"threshold_uncertainty_score":0.01470739,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07049986074682199,"score_gpt":0.3378467916460077,"score_spread":0.2673469308991857,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}