{"id":"W3131952015","doi":"10.1101/2021.02.11.430865","title":"Development and validation of a mouse model of contemporary cannabis smoke exposure","year":2021,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Cannabis and Cannabinoid Research","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"","keywords":"Cannabis; Dronabinol; Lung; Cannabinoid; Smoke; Immune system; Cannabidiol; Medicine; Immunology; Tetrahydrocannabinol; Effects of cannabis; Pharmacology; Inhalation; Delta-9-tetrahydrocannabinol; Macrophage; Carboxyhemoglobin; Smoke inhalation; Biology; Chemistry; Internal medicine; Receptor; In vitro; Anesthesia","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002317394,0.001599708,0.0009502758,0.00316743,0.000960951,0.00112092,0.001279548,0.0022243,0.004105028],"category_scores_gemma":[0.0008855981,0.0009067243,0.001465599,0.0006007035,0.001256293,0.001009734,0.001086301,0.003229981,0.001889383],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007897595,"about_ca_system_score_gemma":0.0008119414,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001303159,"about_ca_topic_score_gemma":0.002424696,"domain_scores_codex":[0.9976333,0.0003884604,0.0002781471,0.0005657107,0.000797399,0.0003368783],"domain_scores_gemma":[0.9981998,0.0002421023,0.0004023811,0.0003481432,0.000402456,0.0004050524],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006640317,0.0009254433,0.001426301,0.000196018,0.00005086622,0.0003118544,0.0001591789,0.0002752024,0.9901771,0.0007123816,0.0003585157,0.004743096],"study_design_scores_gemma":[0.0002686703,0.008036642,0.01204717,0.0002248465,0.0003135873,0.001779652,0.0003450886,0.002940671,0.9527104,0.0006257708,0.02061891,0.00008849033],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8716023,0.004398493,0.1013555,0.001176144,0.0007982493,0.00340518,0.00866358,0.001835966,0.006764583],"genre_scores_gemma":[0.8473398,0.005943806,0.09628057,0.001156408,0.0001856413,0.008467374,0.01137276,0.0007371664,0.02851646],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004105028,"threshold_uncertainty_score":0.01373267,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03591441477569529,"score_gpt":0.2593097689480256,"score_spread":0.2233953541723303,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}