{"id":"W3132047526","doi":"10.15252/emmm.202012005","title":"COCO/DAND5 inhibits developmental and pathological ocular angiogenesis","year":2021,"lang":"en","type":"article","venue":"EMBO Molecular Medicine","topic":"Retinal Diseases and Treatments","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Hôpital Maisonneuve-Rosemont","funders":"Canadian Institutes of Health Research","keywords":"Angiogenesis; Macular degeneration; Choroidal neovascularization; Retinopathy of prematurity; Neovascularization; Coco; Cancer research; Vascular endothelial growth factor A; Medicine; Retinal; Vascular endothelial growth factor; Biology; Ophthalmology; VEGF receptors; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009612984,0.0002035628,0.0003960717,0.0000641067,0.00007031478,0.000009848833,0.00003792433,0.00008710667,0.0003885428],"category_scores_gemma":[0.0002147322,0.0001459996,0.0001011717,0.0002313883,0.0001477222,0.00002535883,0.00007976632,0.00008746608,0.00003384054],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004541488,"about_ca_system_score_gemma":0.0001025698,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001324143,"about_ca_topic_score_gemma":8.141931e-7,"domain_scores_codex":[0.9986655,0.00006367001,0.0002389873,0.0004030158,0.0003779222,0.0002508834],"domain_scores_gemma":[0.9992649,0.00002629504,0.00004140195,0.0001967724,0.0001106916,0.0003599378],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0004648969,0.0009844441,0.2097063,0.0003584113,0.0009087335,0.08168954,0.0005556066,0.000001567736,0.6525728,0.001719787,0.002173956,0.04886398],"study_design_scores_gemma":[0.01112304,0.001425011,0.8310718,0.000949219,0.00151479,0.008206216,0.0008544048,0.00004463629,0.1230271,0.0007413602,0.02051109,0.0005312978],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9738753,0.01689795,0.0003483536,0.002563322,0.00006497993,0.0002492015,0.000006684113,0.00004568316,0.005948532],"genre_scores_gemma":[0.9930671,0.0006009279,0.002343107,0.003184529,0.00007952603,0.00002479537,0.0001859973,0.0000247584,0.0004892132],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6213655,"threshold_uncertainty_score":0.5953689,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01533816790467434,"score_gpt":0.2743081712382798,"score_spread":0.2589700033336054,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}