{"id":"W3132047526","doi":"10.15252/emmm.202012005","title":"COCO/DAND5 inhibits developmental and pathological ocular angiogenesis","year":2021,"lang":"en","type":"article","venue":"EMBO Molecular Medicine","topic":"Retinal Diseases and Treatments","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Hôpital Maisonneuve-Rosemont","funders":"Canadian Institutes of Health Research","keywords":"Angiogenesis; Macular degeneration; Choroidal neovascularization; Retinopathy of prematurity; Neovascularization; Coco; Cancer research; Vascular endothelial growth factor A; Medicine; Retinal; Vascular endothelial growth factor; Biology; Ophthalmology; VEGF receptors; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007633404,0.0001596832,0.0001451295,0.0002791449,0.000126827,0.0001962087,0.0001329653,0.0001496504,0.001284391],"category_scores_gemma":[0.0001232015,0.00004616718,0.0001318471,0.0001162335,0.0001883727,0.00007686237,0.0001374317,0.0002695007,0.0001453119],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002761977,"about_ca_system_score_gemma":0.0002528901,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001631504,"about_ca_topic_score_gemma":0.003744133,"domain_scores_codex":[0.9999267,0.00001181462,0.000004577576,0.00001136024,0.00002122325,0.00002435631],"domain_scores_gemma":[0.999959,0.000007430733,0.000007183784,0.000003690926,0.000006169795,0.000016555],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005646665,0.0002832478,0.0008661786,0.0002401579,0.00002756502,0.0001821859,0.00002498208,0.0002237056,0.9760485,0.0005316538,0.0007323303,0.02027482],"study_design_scores_gemma":[0.00008610368,0.00144855,0.009379361,0.0000326665,0.00004573389,0.0004663683,0.00005640514,0.00149441,0.9691069,0.0001018847,0.01777327,0.000008284984],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9759546,0.0105921,0.002390177,0.0004222144,0.0001649667,0.00006514932,0.0006317035,0.000121198,0.009657799],"genre_scores_gemma":[0.9934859,0.002055233,0.001092942,0.0001266702,0.00001624491,0.0000228549,0.0004653155,0.000008893915,0.002726139],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001631504,"threshold_uncertainty_score":0.00429672,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01533816790467434,"score_gpt":0.2743081712382798,"score_spread":0.2589700033336054,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}