{"id":"W3132104695","doi":"10.1007/s00467-021-04934-y","title":"Population-based studies reveal an additive role of type IV collagen variants in hematuria and albuminuria","year":2021,"lang":"en","type":"review","venue":"Pediatric Nephrology","topic":"Cell Adhesion Molecules Research","field":"Medicine","cited_by":15,"is_retracted":false,"has_abstract":false,"ca_institutions":"Hospital for Sick Children; Toronto General Hospital; Public Health Ontario; University of Toronto; University Health Network","funders":"Canadian Institutes of Health Research; Alport Syndrome Foundation; Nephcure Foundation","keywords":"Alport syndrome; Medicine; Albuminuria; Population; Kidney disease; Missense mutation; Genetics; Nephrology; Genome-wide association study; Glomerulonephritis; Single-nucleotide polymorphism; Internal medicine; Mutation; Kidney; Gene; Biology; Genotype","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006894795,0.0007069612,0.001700398,0.0009114753,0.0001136187,0.0006507511,0.0005763291,0.0006340517,0.001989621],"category_scores_gemma":[0.001219733,0.000161653,0.000990456,0.001641091,0.0002563137,0.0004033095,0.0003984943,0.0008745519,0.0003124317],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002248404,"about_ca_system_score_gemma":0.0007149875,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001450496,"about_ca_topic_score_gemma":0.002270921,"domain_scores_codex":[0.9997457,0.00005862444,0.00003399731,0.00007364549,0.00006782523,0.00002033385],"domain_scores_gemma":[0.9992899,0.0004925483,0.0000958954,0.0000153808,0.00007974017,0.00002655228],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"systematic_review","study_design_scores_codex":[0.0005626401,0.00007696971,0.01351563,0.01457174,0.003709397,0.0005959577,0.00005293321,0.0004746402,0.001659337,0.00206548,0.01077839,0.9519369],"study_design_scores_gemma":[0.0003954605,0.0008292865,0.1777175,0.01785686,0.02362327,0.01239305,0.000412549,0.0008796789,0.002233905,0.01132163,0.7521521,0.0001845218],"study_design_candidate":"systematic_review","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001008869,0.997922,0.000261607,0.000238703,0.0001176766,0.000002466688,0.00007096059,0.00000609421,0.0003715538],"genre_scores_gemma":[0.007956574,0.9905811,0.0005263252,0.00024538,0.0002827533,0.000007018756,0.0001202089,0.000002272575,0.0002784296],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001989621,"threshold_uncertainty_score":0.006655991,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04827145345385763,"score_gpt":0.3820977336713836,"score_spread":0.3338262802175259,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}