{"id":"W3132165990","doi":"10.3390/toxins13020138","title":"Extracts Prepared from a Canadian Toxic Plant Induce Light-Dependent Perinuclear Vacuoles in Human Cells","year":2021,"lang":"en","type":"article","venue":"Toxins","topic":"Nuclear Structure and Function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; University of Lethbridge","funders":"Natural Sciences and Engineering Research Council of Canada; Canada Foundation for Innovation","keywords":"Vacuole; Vacuolization; Biology; Cell biology; Cytoplasm; Lamin; Autophagy; Plant cell; Nucleus; Cell nucleus; Biochemistry; Apoptosis; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00004584807,0.0001215982,0.0001207072,0.00004682251,0.00007517885,0.00003888207,0.0001148647,0.0001899729,0.0003976914],"category_scores_gemma":[0.00001507062,0.000127561,0.00005652761,0.00005953476,0.00001301736,0.000004703908,0.00005872102,0.0001232976,0.00003908242],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005235574,"about_ca_system_score_gemma":0.0001564322,"about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_topic_score_codex":0.0139924,"about_ca_topic_score_gemma":0.255915,"domain_scores_codex":[0.9991348,0.00003989652,0.0001428662,0.0003479068,0.00009326048,0.0002412146],"domain_scores_gemma":[0.9994527,0.000003249187,0.00003058762,0.0003438751,0.00002463204,0.0001449738],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002010386,0.0000319567,0.0005171616,0.000003998112,0.00003180615,0.00009843375,0.0002604045,0.00002291316,0.9961511,0.00004326068,0.002079807,0.0007390299],"study_design_scores_gemma":[0.0003658151,0.00009386693,0.01528748,0.00001414296,0.00001468456,0.00001962082,0.0002888256,0.00001182731,0.8038762,0.00006584034,0.17976,0.0002016585],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9926009,0.0002899155,0.000005108202,0.0001248673,0.0002493085,0.00008093896,0.0001020114,0.00001146724,0.006535445],"genre_scores_gemma":[0.9979948,0.00004170897,0.000133643,0.0003649104,0.0002492917,0.000004284823,0.0002423282,0.00002405757,0.000944933],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2419226,"threshold_uncertainty_score":0.9925735,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00794921522357027,"score_gpt":0.2124885025760842,"score_spread":0.2045392873525139,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}