{"id":"W3132232613","doi":"10.1101/2021.02.25.431980","title":"The plant immune receptors NRG1.1 and ADR1 are calcium influx channels","year":2021,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Toxin Mechanisms and Immunotoxins","field":"Immunology and Microbiology","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill; University of California, San Diego; Connaught Fund; Eberhard Karls Universität Tübingen; National Research Foundation of Korea; Chinese Academy of Sciences; National Research Foundation; Deutsche Forschungsgemeinschaft; Howard Hughes Medical Institute; National Institutes of Health; National Key Laboratory of Plant Molecular Genetics; National Science Foundation","keywords":"Cell biology; Receptor; Immune receptor; Cytoplasm; Biology; Programmed cell death; Biochemistry; Chemistry; Apoptosis","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0009009241,0.0008020884,0.0009352735,0.0001813257,0.0009072176,0.0004404014,0.0008913628,0.001390583,0.0002221837],"category_scores_gemma":[0.0003507678,0.0006696718,0.000263381,0.0002948751,0.000424496,0.0001513483,0.00146666,0.001902881,0.0001752209],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001696243,"about_ca_system_score_gemma":0.0004503923,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001810069,"about_ca_topic_score_gemma":0.00001024061,"domain_scores_codex":[0.9964356,0.0004660878,0.0008136949,0.001150986,0.0001338889,0.0009997461],"domain_scores_gemma":[0.9968876,0.0002015955,0.0006965094,0.001726069,0.0003759146,0.0001122859],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007685802,0.0001113287,0.0004973905,0.0001336415,0.0005766885,0.00004336789,0.00005517543,0.000006161331,0.9967831,0.0007452127,0.0009598878,0.00001116365],"study_design_scores_gemma":[0.0008856347,0.00009898956,0.02174772,0.0006260388,0.000151697,3.274349e-7,0.0001005452,0.0000125666,0.8925666,0.000003982514,0.08287957,0.0009262858],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9394353,0.04551436,0.0002942225,0.0004886829,0.01249759,0.0009000803,0.0004989873,0.0003612297,0.000009543412],"genre_scores_gemma":[0.9946963,0.003830313,0.0003021179,0.0002452804,0.0002782532,0.0003007358,0.000005462416,0.0001480414,0.0001935514],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1042165,"threshold_uncertainty_score":0.9999058,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01496046522841854,"score_gpt":0.2064652244641715,"score_spread":0.191504759235753,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}