{"id":"W3132270960","doi":"10.1093/clinchem/hvab008","title":"Development and Validation of Measurement Traceability for In Situ Immunoassays","year":2021,"lang":"en","type":"article","venue":"Clinical Chemistry","topic":"Advanced Biosensing Techniques and Applications","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan; Saskatchewan Health Authority","funders":"National Center for Advancing Translational Sciences; National Cancer Institute; National Institutes of Health","keywords":"Traceability; Analyte; Gold standard (test); Quality assurance; NIST; Standardization; Computer science; External quality assessment; Immunoassay; Data mining; Mathematics; Pathology; Medicine; Chromatography; Statistics; Chemistry; Software engineering","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.04578009,0.002260158,0.00120367,0.003334599,0.001110819,0.003275592,0.004474672,0.003211926,0.001952605],"category_scores_gemma":[0.05200494,0.00100579,0.001531553,0.001584068,0.003261505,0.002492312,0.002885794,0.003753208,0.001844818],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002224488,"about_ca_system_score_gemma":0.004268344,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001502469,"about_ca_topic_score_gemma":0.001359642,"domain_scores_codex":[0.9512643,0.01779506,0.002740375,0.005722461,0.02153302,0.0009448411],"domain_scores_gemma":[0.9530019,0.01127858,0.004969583,0.009736013,0.02025218,0.0007618137],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003775173,0.0007537025,0.01718397,0.0009657831,0.0002551429,0.0002812585,0.0007666175,0.007060394,0.8008991,0.01474527,0.003255475,0.1534558],"study_design_scores_gemma":[0.00006294844,0.001336736,0.0061502,0.0002713483,0.0001625295,0.0009015285,0.0001994968,0.02576663,0.9294399,0.004144326,0.0314598,0.000104488],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"methods","genre_scores_codex":[0.03328027,0.001094877,0.9586117,0.0007941896,0.0003595906,0.0009195779,0.0003456359,0.001728606,0.002865459],"genre_scores_gemma":[0.1879789,0.001274417,0.8029226,0.0008733592,0.000240287,0.00155902,0.001423441,0.0005419861,0.003185878],"genre_candidate":"methods","genre_consensus":"methods","teacher_disagreement_score":0.04578009,"threshold_uncertainty_score":0.2421111,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06873678292303945,"score_gpt":0.3642390036614839,"score_spread":0.2955022207384445,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}