{"id":"W3132362195","doi":"10.1158/1538-7445.sabcs20-ps10-14","title":"Abstract PS10-14: Efficacy and safety of palbociclib (PAL) in patients (pts) with estrogen receptor-positive (ER+)/human epidermal growth factor receptor 2-negative (HER2-) advanced breast cancer (ABC) with preexisting conditions: A post hoc analysis of PALOMA-2","year":2021,"lang":"en","type":"article","venue":"Cancer Research","topic":"Advanced Breast Cancer Therapies","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta; Spinal Cord Injury BC","funders":"","keywords":"Medicine; Neutropenia; Internal medicine; Adverse effect; Breast cancer; Cancer; Placebo; Palbociclib; Estrogen receptor; Oncology; Gastroenterology; Metastatic breast cancer; Toxicity; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001429128,0.001075269,0.001576749,0.0002955009,0.0002254892,0.0006662818,0.0006176367,0.0005325889,0.007326117],"category_scores_gemma":[0.001217351,0.0003104146,0.001828252,0.0003037844,0.000592945,0.0006791526,0.0003852298,0.002219639,0.0008492444],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007788319,"about_ca_system_score_gemma":0.001376875,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008521248,"about_ca_topic_score_gemma":0.002161238,"domain_scores_codex":[0.9994819,0.0002832749,0.00003023464,0.00007544462,0.00005087769,0.0000783064],"domain_scores_gemma":[0.9992502,0.0002112243,0.0001872615,0.00006727035,0.00006260092,0.0002213502],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.955304,0.005413566,0.006814785,0.0004370862,0.001756307,0.00005116768,0.00004682612,0.001074197,0.006973935,0.00006196806,0.001395451,0.02067081],"study_design_scores_gemma":[0.5109629,0.4314717,0.0459039,0.00004382855,0.003114786,0.0001378317,0.00006940563,0.001741099,0.004156062,0.0001702013,0.00219631,0.00003204538],"study_design_candidate":"meta_analysis","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.995692,0.0007100351,0.0001796093,0.0001765555,0.00004511209,0.0006684593,0.001367213,0.00003879926,0.00112232],"genre_scores_gemma":[0.994186,0.0004283922,0.0002994447,0.0002320596,0.00009685104,0.0007014548,0.002336301,0.00001394134,0.001705442],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007326117,"threshold_uncertainty_score":0.02450836,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02789522536321866,"score_gpt":0.36227043587781,"score_spread":0.3343752105145913,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}