{"id":"W3132478680","doi":"10.1186/s13058-021-01401-2","title":"Identification of MFGE8 and KLK5/7 as mediators of breast tumorigenesis and resistance to COX-2 inhibition","year":2021,"lang":"en","type":"article","venue":"Breast Cancer Research","topic":"Phagocytosis and Immune Regulation","field":"Immunology and Microbiology","cited_by":26,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; McGill University Health Centre","funders":"Canadian Institutes of Health Research","keywords":"Breast cancer; Cancer research; Triple-negative breast cancer; Cancer; Carcinogenesis; Gene silencing; Medicine; Biology; Oncology; Internal medicine; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006253482,0.00008382067,0.0002176387,0.0001826606,0.0001259959,0.0000158397,0.00007219864,0.00009862274,0.0001952722],"category_scores_gemma":[0.00007954922,0.00008200815,0.00002894106,0.0004492943,0.0002940524,0.0001118242,0.000115769,0.0001208465,0.00001442552],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006075091,"about_ca_system_score_gemma":0.0002079974,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005419677,"about_ca_topic_score_gemma":0.0002222183,"domain_scores_codex":[0.9987656,0.0002710292,0.0003301269,0.0002834385,0.0001327586,0.000216986],"domain_scores_gemma":[0.9988868,0.00009999397,0.0001083533,0.0002255772,0.0006421803,0.00003711826],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003687677,0.00006747172,0.008080534,0.0001284405,0.00004719289,0.000001458712,0.0003609559,0.000001037697,0.9799702,0.001286231,0.0005631909,0.009124547],"study_design_scores_gemma":[0.0004227499,0.00002395906,0.4190935,0.0001304678,0.00001212294,0.00007660268,0.0002825634,0.000001295483,0.5791615,0.0002915072,0.0004470079,0.00005666478],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9903775,0.007285226,0.00001997378,0.001610388,0.0000973224,0.0001858315,0.000288697,0.000007628758,0.0001273754],"genre_scores_gemma":[0.99789,0.0009888668,0.00001471844,0.00001534599,0.00002579278,0.00004683802,0.00004461674,0.00001078572,0.0009630157],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.411013,"threshold_uncertainty_score":0.3344195,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01958967147555377,"score_gpt":0.3275860681982374,"score_spread":0.3079963967226836,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}