{"id":"W3132483202","doi":"10.1016/j.celrep.2021.108781","title":"Functional connections between cell cycle and proteostasis in the regulation of Candida albicans morphogenesis","year":2021,"lang":"en","type":"review","venue":"Cell Reports","topic":"Antifungal resistance and susceptibility","field":"Medicine","cited_by":33,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"National Institute of Allergy and Infectious Diseases; Institute of Infection and Immunity; Canadian Institutes of Health Research; National Institutes of Health; Canada Research Chairs; Canadian Institute for Advanced Research","keywords":"Proteostasis; Biology; Cell biology; Morphogenesis; Candida albicans; Transcription factor; Cell cycle; Corpus albicans; HSF1; Heat shock protein; Cell; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002697766,0.0005701478,0.0008741902,0.001494585,0.0002254658,0.0009869745,0.0005014106,0.0006063993,0.002468672],"category_scores_gemma":[0.0003856852,0.0001763593,0.0003071885,0.001765023,0.0002642857,0.0007931065,0.0005176377,0.0009306299,0.001152703],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004510452,"about_ca_system_score_gemma":0.0007385172,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006838028,"about_ca_topic_score_gemma":0.00124088,"domain_scores_codex":[0.9998962,0.00001401297,0.0000171879,0.00001695283,0.00004351731,0.00001221632],"domain_scores_gemma":[0.9998832,0.00004020168,0.00002237441,0.000003248937,0.00003576972,0.00001515119],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00009287683,0.00004363703,0.0002668645,0.01945464,0.0001202902,0.0002696222,0.00007348978,0.0002813285,0.00518083,0.003984577,0.02125445,0.9489774],"study_design_scores_gemma":[0.00001784327,0.00009256432,0.001881748,0.003425022,0.000177203,0.001535109,0.0000755328,0.0001083905,0.001638978,0.002593326,0.9884273,0.00002695826],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001754012,0.9988161,0.00007536877,0.0001309474,0.00007964188,0.000002352115,0.00001841125,0.000005919513,0.000695869],"genre_scores_gemma":[0.001016855,0.9982644,0.0001311968,0.00007771458,0.00007529231,0.000003489315,0.00003178014,9.985297e-7,0.0003983555],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002468672,"threshold_uncertainty_score":0.008258522,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04743335918307701,"score_gpt":0.3065828311691557,"score_spread":0.2591494719860787,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}