{"id":"W3132483202","doi":"10.1016/j.celrep.2021.108781","title":"Functional connections between cell cycle and proteostasis in the regulation of Candida albicans morphogenesis","year":2021,"lang":"en","type":"review","venue":"Cell Reports","topic":"Antifungal resistance and susceptibility","field":"Medicine","cited_by":33,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"National Institute of Allergy and Infectious Diseases; Institute of Infection and Immunity; Canadian Institutes of Health Research; National Institutes of Health; Canada Research Chairs; Canadian Institute for Advanced Research","keywords":"Proteostasis; Biology; Cell biology; Morphogenesis; Candida albicans; Transcription factor; Cell cycle; Corpus albicans; HSF1; Heat shock protein; Cell; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006527989,0.000213812,0.001083108,0.0001203303,0.00008224414,0.00001438037,0.0000420044,0.0002251823,0.0002635671],"category_scores_gemma":[0.0001568942,0.000148142,0.0003042915,0.0004257453,0.00009965074,0.00003377407,0.00003083835,0.0002661406,0.000002303071],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000103279,"about_ca_system_score_gemma":0.0006937243,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002898048,"about_ca_topic_score_gemma":0.0001260182,"domain_scores_codex":[0.9980544,0.0001341958,0.0008366921,0.0004589323,0.0003498403,0.0001659145],"domain_scores_gemma":[0.9984528,0.0002332632,0.0005132882,0.0005990459,0.0001292424,0.00007231941],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00007473493,0.001243098,0.2418141,0.08618221,0.0005212903,0.001722518,0.0007265819,0.00001478223,0.0008134329,0.000076458,0.007510072,0.6593007],"study_design_scores_gemma":[0.0004014231,0.0001506267,0.1294504,0.006614712,0.003232724,0.0006168101,0.0004980469,0.000002988443,0.0005955963,0.0001021815,0.857908,0.0004264323],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.03986548,0.9556247,0.00004357696,0.00004663246,0.00009192331,0.001291967,0.0000346584,0.00001133174,0.00298971],"genre_scores_gemma":[0.1474285,0.8493773,0.00009074246,0.00001768766,0.000146208,0.0001235374,0.0005417112,0.00002844873,0.002245882],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.8503979,"threshold_uncertainty_score":0.6041058,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04743335918307701,"score_gpt":0.3065828311691557,"score_spread":0.2591494719860787,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}