{"id":"W3132551129","doi":"10.1016/j.exer.2021.108500","title":"Matrix metalloproteinases and their inhibitors in Fuchs endothelial corneal dystrophy","year":2021,"lang":"en","type":"article","venue":"Experimental Eye Research","topic":"Corneal surgery and disorders","field":"Medicine","cited_by":15,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université Laval; Centre hospitalier de l'Université Laval; Université de Montréal; Hôpital Maisonneuve-Rosemont; Hôpital du Saint-Sacrement","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Matrix metalloproteinase; Extracellular matrix; Zymography; Descemet's membrane; Fibronectin; Laminin; Proteases; Cell biology; Chemistry; Biology; Molecular biology; Biochemistry; Cornea; Enzyme","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000446809,0.0001534988,0.0002996282,0.0002159273,0.0001295609,0.00005335122,0.00006448319,0.00008374752,0.0007202065],"category_scores_gemma":[0.0001703103,0.0001271424,0.00009455862,0.0004958835,0.0002598138,0.00009990801,0.0002190599,0.0003891605,0.00005252888],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001247865,"about_ca_system_score_gemma":0.0002255616,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000406842,"about_ca_topic_score_gemma":0.00003467317,"domain_scores_codex":[0.9982225,0.0002301268,0.0002362811,0.0004015949,0.0004335307,0.0004759555],"domain_scores_gemma":[0.9992707,0.0001668485,0.00002053885,0.0002367235,0.00008107406,0.0002241087],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008159718,0.0008330126,0.01241615,0.00006308572,0.00003715691,0.0009721894,0.001080468,9.643527e-7,0.975921,0.0006674586,0.0003867896,0.006805765],"study_design_scores_gemma":[0.001901911,0.0004471386,0.004145674,0.00009564823,0.000003560595,0.00009077733,0.009923925,0.00006313411,0.9748999,0.0001760907,0.008105143,0.0001470393],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9805849,0.01229866,0.000003436307,0.0005772124,0.00009989132,0.0004168678,0.0000131937,0.00002958162,0.00597624],"genre_scores_gemma":[0.9977005,0.0001902502,0.0001241999,0.00006365481,0.000150682,0.0001011454,0.00002503175,0.00002384235,0.001620731],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01711555,"threshold_uncertainty_score":0.7885756,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05092819648225785,"score_gpt":0.3916576970855687,"score_spread":0.3407295006033109,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}