{"id":"W3132551129","doi":"10.1016/j.exer.2021.108500","title":"Matrix metalloproteinases and their inhibitors in Fuchs endothelial corneal dystrophy","year":2021,"lang":"en","type":"article","venue":"Experimental Eye Research","topic":"Corneal surgery and disorders","field":"Medicine","cited_by":15,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université Laval; Centre hospitalier de l'Université Laval; Université de Montréal; Hôpital Maisonneuve-Rosemont; Hôpital du Saint-Sacrement","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Matrix metalloproteinase; Extracellular matrix; Zymography; Descemet's membrane; Fibronectin; Laminin; Proteases; Cell biology; Chemistry; Biology; Molecular biology; Biochemistry; Cornea; Enzyme","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004695493,0.0002855503,0.0002819658,0.0008273543,0.0002549138,0.0004713808,0.0002403407,0.000401447,0.0008169256],"category_scores_gemma":[0.0004489976,0.0001525605,0.0001820919,0.0003575938,0.0003635026,0.0004121922,0.0002131941,0.0004979983,0.00009257205],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003885277,"about_ca_system_score_gemma":0.0002911971,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001297902,"about_ca_topic_score_gemma":0.001017378,"domain_scores_codex":[0.9998481,0.00003908089,0.00002975296,0.00001497994,0.00004164247,0.00002637256],"domain_scores_gemma":[0.9998239,0.0000608087,0.00004782461,0.00001080096,0.00001615132,0.00004059666],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.03591364,0.002000296,0.09454512,0.001993188,0.0006165517,0.0298181,0.001194131,0.00511007,0.5199317,0.03130032,0.00706693,0.27051],"study_design_scores_gemma":[0.001595212,0.004060155,0.4625982,0.0002316441,0.0007600324,0.05266423,0.001021157,0.01591133,0.3812903,0.0118822,0.06784849,0.0001370257],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8839104,0.1080442,0.00185082,0.0007314453,0.0002110658,0.00002800065,0.0001908647,0.00004978495,0.00498349],"genre_scores_gemma":[0.9844094,0.01247492,0.0007221242,0.00004866658,0.0001089751,0.00001564099,0.0000819398,0.000003212169,0.002135075],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001297902,"threshold_uncertainty_score":0.002819002,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05092819648225785,"score_gpt":0.3916576970855687,"score_spread":0.3407295006033109,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}