{"id":"W3132604873","doi":"10.1016/j.bpj.2020.11.1192","title":"The Mechanics of Prostate Cancer Progression: Toward Characterizing Metastatic Potential as a Function of Cell Contractility","year":2021,"lang":"en","type":"article","venue":"Biophysical Journal","topic":"Cellular Mechanics and Interactions","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University","funders":"","keywords":"LNCaP; Contractility; DU145; Cancer cell; Tumor microenvironment; Prostate cancer; Cell; Tractive force; Cancer; Cancer research; Chemistry; Cell biology; Medicine; Biology; Internal medicine; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004565269,0.000345627,0.0002500256,0.0006539549,0.0003723906,0.0008789729,0.000348016,0.0003838973,0.0007203031],"category_scores_gemma":[0.0008207326,0.0003558148,0.0001521683,0.0005675201,0.0006719704,0.0009990109,0.0004003122,0.00081409,0.0002152279],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003619995,"about_ca_system_score_gemma":0.0003399746,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001456307,"about_ca_topic_score_gemma":0.001654296,"domain_scores_codex":[0.9998813,0.00003018074,0.000006124704,0.00002173518,0.00004125926,0.00001947298],"domain_scores_gemma":[0.9997329,0.0001056294,0.00005788293,0.00003094866,0.00003365025,0.00003891807],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001563069,0.00006554582,0.02545021,0.0001055642,0.00003885529,0.0001136087,0.0002404688,0.01415229,0.9298846,0.01041994,0.0004137216,0.01895891],"study_design_scores_gemma":[0.00002417235,0.0002985614,0.2709205,0.00004777602,0.0000733586,0.001163369,0.0004946954,0.356537,0.3505513,0.01550911,0.004240339,0.0001399156],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9396105,0.002510633,0.05343186,0.0005567916,0.00003148294,0.00002137554,0.000276145,0.0001458348,0.003415328],"genre_scores_gemma":[0.9958227,0.0008853089,0.002661122,0.0000427128,0.00002174092,0.00001855936,0.00005160616,0.0000230766,0.0004733191],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001456307,"threshold_uncertainty_score":0.002895713,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01140737703855486,"score_gpt":0.2715259915310002,"score_spread":0.2601186144924453,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}