{"id":"W3132700492","doi":"10.1158/1538-7445.sabcs20-pd2-04","title":"Abstract PD2-04: Updated overall survival (OS) results from the phase III MONALEESA-7 trial of pre- or perimenopausal patients with hormone receptor positive/human epidermal growth factor receptor 2 negative (HR+/HER2−) advanced breast cancer (ABC) treated with endocrine therapy (ET) ± ribociclib","year":2021,"lang":"en","type":"article","venue":"Cancer Research","topic":"Advanced Breast Cancer Therapies","field":"Medicine","cited_by":30,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"","keywords":"Medicine; Letrozole; Internal medicine; Anastrozole; Oncology; Tamoxifen; Hazard ratio; Placebo; Randomized controlled trial; Progression-free survival; Goserelin; Breast cancer; Chemotherapy; Gynecology; Cancer; Confidence interval; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000545991,0.0008357551,0.001443772,0.0002068906,0.0005305751,0.0001142202,0.0005767991,0.0001949909,0.004798394],"category_scores_gemma":[0.000255047,0.0004995484,0.0001735982,0.001317508,0.001141538,0.0007632026,0.0001807371,0.001515997,0.00001101381],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001244206,"about_ca_system_score_gemma":0.002330445,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01599763,"about_ca_topic_score_gemma":0.001716303,"domain_scores_codex":[0.9926095,0.001015742,0.001108902,0.00153591,0.002391191,0.001338733],"domain_scores_gemma":[0.9925162,0.001340312,0.0007095658,0.001099228,0.003793888,0.0005408268],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.7117016,0.002799718,0.003512538,0.00004508739,0.002036202,0.0001066924,0.002472164,0.00005522335,0.2578962,0.00002892756,0.0009541477,0.01839148],"study_design_scores_gemma":[0.3973829,0.00911347,0.3570527,0.0008894996,0.0001568099,0.00001590127,0.0009131141,0.000009779624,0.2308801,0.00003576185,0.00277124,0.0007786866],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9739811,0.00145203,0.00001950444,0.003874824,0.0001984417,0.003986511,0.01609365,0.0001221348,0.0002717919],"genre_scores_gemma":[0.9897844,0.002641441,0.000436387,0.0002718696,0.0008125776,0.001098986,0.003179542,0.0002417577,0.001533007],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3535402,"threshold_uncertainty_score":0.9997456,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04548641285416216,"score_gpt":0.3831915911177023,"score_spread":0.3377051782635401,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}