{"id":"W3132756055","doi":"10.1128/msphere.01250-20","title":"Aspergillus fumigatus Strain-Specific Conidia Lung Persistence Causes an Allergic Broncho-Pulmonary Aspergillosis-Like Disease Phenotype","year":2021,"lang":"en","type":"article","venue":"mSphere","topic":"Antifungal resistance and susceptibility","field":"Medicine","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Allergy and Infectious Diseases; National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; Dartmouth College; National Institute of General Medical Sciences; Canadian Institute for Advanced Research; Memorial Sloan-Kettering Cancer Center; Cystic Fibrosis Foundation; National Cancer Institute; National Institutes of Health; National Science Foundation","keywords":"Allergic bronchopulmonary aspergillosis; Aspergillus fumigatus; Cystic fibrosis; Aspergillus; Aspergillosis; Pulmonary aspergillosis; Lung; Immunology; Medicine; Disease; Phenotype; Fungus; Microbiology; Lung disease; Biology; Pathology; Immunoglobulin E; Antibody; Internal medicine","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001442523,0.0002742169,0.0002275012,0.0002292027,0.0002099509,0.0003079488,0.0001163558,0.0003537356,0.002507757],"category_scores_gemma":[0.0002630534,0.00008907473,0.0001543815,0.0001195209,0.0002669285,0.0001740798,0.0002051099,0.0006705198,0.0004854505],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001374988,"about_ca_system_score_gemma":0.0001309167,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004400274,"about_ca_topic_score_gemma":0.0009206241,"domain_scores_codex":[0.9998382,0.00002936142,0.0000154351,0.00002978977,0.00004469651,0.0000425699],"domain_scores_gemma":[0.9997666,0.00004697148,0.00006747593,0.00002624584,0.00002241945,0.00007028133],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002755924,0.0002383262,0.02082778,0.00006859291,0.00002997231,0.006602193,0.00009193857,0.00005964589,0.9591562,0.0006026493,0.0009458751,0.01110131],"study_design_scores_gemma":[0.00008217474,0.002055632,0.5233268,0.00006169524,0.00009707532,0.1135678,0.0007744987,0.001345312,0.3410303,0.001352658,0.01627525,0.0000307757],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9936294,0.0008803239,0.0009744205,0.0004798219,0.00005314964,0.00001911087,0.0002003547,0.00008170705,0.003681621],"genre_scores_gemma":[0.9980652,0.0002235271,0.0003763851,0.0001365129,0.00002655385,0.000005838839,0.0001395655,0.0000137116,0.001012879],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002507757,"threshold_uncertainty_score":0.008389235,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03244788078379739,"score_gpt":0.2687327372105947,"score_spread":0.2362848564267973,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}