{"id":"W3132829686","doi":"","title":"Non-Redundant Activity of GSK-3α and GSK-3β in T Cell-Mediated Tumour Rejection","year":2021,"lang":"en","type":"article","venue":"SSRN Electronic Journal","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"","keywords":"GSK-3; Gene isoform; CD8; Granzyme B; Cytotoxic T cell; Gene knockdown; Granzyme; Cancer research; GSK3B; T cell; Biology; Chemistry; Immune system; Cell biology; Molecular biology; Kinase; Immunology; Apoptosis; Perforin; Gene; Biochemistry; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001808802,0.0005227241,0.0002634296,0.0002818518,0.0001075309,0.0004024889,0.0001725145,0.0002442498,0.001022355],"category_scores_gemma":[0.0001399649,0.0002020757,0.0004904933,0.0001375212,0.0003809905,0.0002644634,0.0002244376,0.0008013796,0.0003790274],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002111907,"about_ca_system_score_gemma":0.000256023,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001599316,"about_ca_topic_score_gemma":0.0002610088,"domain_scores_codex":[0.9998487,0.00002472897,0.00002225978,0.00003059818,0.00003194321,0.0000417275],"domain_scores_gemma":[0.9998497,0.00001346278,0.00006483629,0.00002196851,0.000007739361,0.00004225465],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003887109,0.00003465925,0.0004002,0.00006467776,0.00001293991,0.00011232,0.00001080073,0.0001534025,0.9964656,0.0002070324,0.00003619326,0.002113429],"study_design_scores_gemma":[0.0001740323,0.0007213457,0.01236051,0.00002986542,0.00008131364,0.001282788,0.00005616646,0.001583894,0.9805999,0.0004703688,0.002628277,0.0000114312],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9913331,0.003928871,0.002614759,0.0001652002,0.00006285546,0.00002540637,0.000231814,0.0001166527,0.001521332],"genre_scores_gemma":[0.9969777,0.000932402,0.0007723882,0.00003877437,0.00001192058,0.0000232702,0.0001126273,0.00001246006,0.00111852],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001022355,"threshold_uncertainty_score":0.003420174,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005378968336752128,"score_gpt":0.2225101723824595,"score_spread":0.2171312040457073,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}