{"id":"W3132993655","doi":"10.21203/rs.3.rs-124700/v2","title":"Precision Medicine, Developmental Plasticity and Prevention of Non-Communicable Disease","year":2021,"lang":"en","type":"preprint","venue":"Research Square","topic":"Birth, Development, and Health","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Sinai Health System; Lunenfeld-Tanenbaum Research Institute","funders":"Canadian Institutes of Health Research; Raine Medical Research Foundation; Safe Work Australia; University of Notre Dame Australia; Murdoch University; Government of Western Australia; Edith Cowan University; Curtin University of Technology; National Health and Medical Research Council; Women and Infants Research Foundation; Department of Health, Government of Western Australia; Australian Government; Medical Research Council; University of Notre Dame","keywords":"Breastfeeding; Non-communicable disease; Disease; Obesity; Medicine; Medical genetics; Gerontology; Pediatrics; Physiology; Endocrinology; Biology; Internal medicine; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00375488,0.0003259693,0.0005943624,0.0009108837,0.0003254848,0.001363175,0.0005350681,0.0009847634,0.006605848],"category_scores_gemma":[0.009929554,0.000114083,0.0004285717,0.0007865536,0.00124145,0.0006095559,0.0009789346,0.001028041,0.0006339472],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000807052,"about_ca_system_score_gemma":0.001552475,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001704772,"about_ca_topic_score_gemma":0.001824092,"domain_scores_codex":[0.9987366,0.0006820693,0.00005103528,0.0002435133,0.0002047266,0.00008203598],"domain_scores_gemma":[0.9953157,0.002820897,0.0007487522,0.0004836205,0.000378792,0.0002522661],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.0009169406,0.0003159039,0.077225,0.002537688,0.001731386,0.0006511518,0.0006213156,0.00553493,0.00937192,0.09023293,0.0431879,0.767673],"study_design_scores_gemma":[0.0005346465,0.001402535,0.234211,0.004557425,0.001256923,0.002159521,0.0008124824,0.007138689,0.01933861,0.438871,0.2895842,0.0001330726],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"genre_codex":"review","genre_gemma":"empirical","genre_scores_codex":[0.2308076,0.4012444,0.106085,0.1771219,0.004254083,0.0001916767,0.009355195,0.001422929,0.06951722],"genre_scores_gemma":[0.8370517,0.09982256,0.04115034,0.01035404,0.00189017,0.0001768822,0.001545939,0.0001075471,0.007900603],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.006605848,"threshold_uncertainty_score":0.02209872,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1023610780309636,"score_gpt":0.4416676093854827,"score_spread":0.339306531354519,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}