{"id":"W3133060081","doi":"10.18433/jpps31305","title":"The CYP2R1 Enzyme: Structure, Function, Enzymatic Properties and Genetic Polymorphism","year":2021,"lang":"en","type":"article","venue":"Journal of Pharmacy & Pharmaceutical Sciences","topic":"Pharmacogenetics and Drug Metabolism","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Centre National de la Recherche Scientifique; Ministry of Higher Education, Malaysia","keywords":"Biology; Single-nucleotide polymorphism; Genetics; Gene; Genotype","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000465489,0.0004042225,0.0005960424,0.0005415448,0.0001710307,0.0007276762,0.0002830407,0.000425184,0.001826005],"category_scores_gemma":[0.000522623,0.0001303862,0.0002739334,0.001355428,0.0002791473,0.0002898045,0.0002010109,0.0005167402,0.00139731],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003157351,"about_ca_system_score_gemma":0.0001563361,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009663919,"about_ca_topic_score_gemma":0.0004591816,"domain_scores_codex":[0.9995965,0.00009749946,0.00003317771,0.0001472506,0.0001046162,0.00002095901],"domain_scores_gemma":[0.9997182,0.00006007213,0.0001169251,0.00001999097,0.00005799083,0.00002672619],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001893709,0.0003352191,0.1715488,0.001872003,0.0006351576,0.002048748,0.0004020029,0.001603857,0.165976,0.004168388,0.01204495,0.6374713],"study_design_scores_gemma":[0.0001312681,0.001012586,0.7350481,0.0001981239,0.0004338456,0.0244295,0.0001900923,0.002131295,0.04765844,0.002830875,0.1858356,0.0001003131],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.5846494,0.3756497,0.01576027,0.004612294,0.0002303657,0.0001117548,0.005930109,0.0005126317,0.01254356],"genre_scores_gemma":[0.9237917,0.05449461,0.005923576,0.0004197106,0.0007549725,0.00007721659,0.005263292,0.00008283554,0.009192024],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001826005,"threshold_uncertainty_score":0.006108642,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.164370978671245,"score_gpt":0.4248624400500307,"score_spread":0.2604914613787858,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}