{"id":"W3133088824","doi":"10.1139/gen-2020-0139","title":"The role of chromatin organizer Satb1 in shaping TCR repertoire in adult thymus","year":2021,"lang":"en","type":"article","venue":"Genome","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Natural Science Foundation of China","keywords":"T-cell receptor; Biology; Gene rearrangement; Repertoire; Gene; Recombinase; CD8; Chromatin; Genetics; Recombination-activating gene; Thymocyte; T cell; Molecular biology; Cell biology; Antigen; Recombination; Immune system","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008148397,0.0002208703,0.000125192,0.0002683319,0.000164905,0.0002414532,0.0001888626,0.0002374987,0.001273862],"category_scores_gemma":[0.0001268364,0.0001630869,0.0001184767,0.0001262068,0.0002098031,0.0001983279,0.0002729474,0.0003060636,0.0003413846],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001525683,"about_ca_system_score_gemma":0.0001181434,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004528487,"about_ca_topic_score_gemma":0.0007560088,"domain_scores_codex":[0.9999087,0.00001016133,0.00000529486,0.00002946481,0.00002228665,0.00002408962],"domain_scores_gemma":[0.9998691,0.00001500047,0.00004700753,0.00001095214,0.00001694329,0.00004105669],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002303029,0.000002855742,0.001326891,0.0000121173,0.000001653556,0.0000456216,0.00001268308,0.00002364144,0.9976543,0.00003657714,0.000009116214,0.0008515246],"study_design_scores_gemma":[0.00001877441,0.0002205206,0.1762332,0.00002330574,0.00004076993,0.001453257,0.000150376,0.00200304,0.816557,0.0002119139,0.003076468,0.00001139193],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9956233,0.001902296,0.001662944,0.00003736464,0.000007124363,0.000004499605,0.0001515792,0.00004009834,0.0005708867],"genre_scores_gemma":[0.9976022,0.0005345051,0.0006696599,0.00002399406,0.000005272329,0.000006339121,0.0002664405,0.00001123469,0.0008804529],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001273862,"threshold_uncertainty_score":0.004261494,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007440692726175833,"score_gpt":0.1970061891686347,"score_spread":0.1895654964424588,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}