{"id":"W3133115881","doi":"10.1158/1538-7445.sabcs20-gs4-09","title":"Abstract GS4-09: Correlative studies of the breast cancer index (HOXB13/IL17BR) and ER, PR, AR, AR/ER ratio and Ki67 for prediction of extended endocrine benefit: A trans-aTTom study","year":2021,"lang":"en","type":"article","venue":"Cancer Research","topic":"Breast Cancer Treatment Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Cancer Research","funders":"","keywords":"Biomarker; Breast cancer; Medicine; Tamoxifen; Estrogen receptor; Internal medicine; Oncology; Tissue microarray; Cancer; Androgen receptor; Progesterone receptor; Immunohistochemistry; Proportional hazards model; Prostate cancer; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.005774023,0.001097427,0.001090834,0.0004877802,0.0002474685,0.0005903842,0.0008256056,0.0005847558,0.002829435],"category_scores_gemma":[0.003177282,0.0003481783,0.00137438,0.0005504676,0.0009314833,0.0005484641,0.0008037147,0.00106497,0.0004765534],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005237622,"about_ca_system_score_gemma":0.0008172274,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007745406,"about_ca_topic_score_gemma":0.001209884,"domain_scores_codex":[0.9981799,0.001273832,0.0000886106,0.0002038997,0.0001750794,0.00007862992],"domain_scores_gemma":[0.9963608,0.001159504,0.0008586565,0.0007481048,0.0002595463,0.0006133482],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"observational","study_design_scores_codex":[0.6742432,0.005155311,0.2603204,0.0005316366,0.006073378,0.0001610466,0.0001708615,0.001826188,0.01350554,0.0002689444,0.001414326,0.03632923],"study_design_scores_gemma":[0.08854999,0.2488363,0.6231176,0.0001232517,0.01306832,0.001006105,0.0002132223,0.006746866,0.01127319,0.0009808195,0.00595622,0.0001281002],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9970351,0.001031298,0.0003296643,0.0001270809,0.00003244316,0.0001466574,0.000644521,0.00002053558,0.0006326233],"genre_scores_gemma":[0.9971104,0.0002237852,0.000491298,0.0001389737,0.00008547129,0.0001343777,0.001192532,0.00001093147,0.0006122156],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005774023,"threshold_uncertainty_score":0.03053629,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06179371606217465,"score_gpt":0.3955278372658432,"score_spread":0.3337341212036686,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}