{"id":"W3133158994","doi":"10.1016/j.molmet.2021.101191","title":"Sensory neurons derived from diabetic rats exhibit deficits in functional glycolysis and ATP that are ameliorated by IGF-1","year":2021,"lang":"en","type":"article","venue":"Molecular Metabolism","topic":"Pain Mechanisms and Treatments","field":"Medicine","cited_by":26,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba; St. Boniface Hospital","funders":"Canadian Institutes of Health Research","keywords":"Glycolysis; Oligomycin; Neurite; Dorsal root ganglion; Oxidative phosphorylation; Adenosine triphosphate; Mitochondrion; Internal medicine; Endocrinology; ATP synthase; Biology; Chemistry; Cell biology; Biochemistry; Neuroscience; Medicine; Metabolism; Sensory system; ATPase; Enzyme; In vitro","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000079845,0.0002661002,0.0005371788,0.0001224909,0.00007416509,0.00004340708,0.00004491526,0.0001171045,0.0001991341],"category_scores_gemma":[0.0001253114,0.0002538633,0.0001193766,0.0003584936,0.00004275427,0.00006084457,0.00006813592,0.0002123328,0.00003735514],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003579931,"about_ca_system_score_gemma":0.00008190501,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001167904,"about_ca_topic_score_gemma":0.00003422782,"domain_scores_codex":[0.9983078,0.0002308971,0.0002244486,0.0005697391,0.0003473357,0.0003198266],"domain_scores_gemma":[0.9991942,0.0000653506,0.00008659804,0.0003528043,0.00009978507,0.0002012537],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007318828,0.0002690968,0.008844165,0.0000149995,0.0002341792,0.00215951,0.0001141906,0.00001740185,0.9866748,0.00005301406,0.0001414557,0.001403986],"study_design_scores_gemma":[0.003443916,0.00002866975,0.2941013,0.00006892112,0.0006080825,0.00003801167,0.0002057114,0.0002574315,0.6990243,0.0003432767,0.001635366,0.0002450056],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9802238,0.01716504,0.001203117,0.0007403245,0.0001730796,0.0002501336,0.0001058289,0.00004928845,0.00008936066],"genre_scores_gemma":[0.9954225,0.0003412237,0.001171138,0.002260515,0.00003728701,0.00004870087,0.0003391786,0.00004736332,0.0003320665],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2876505,"threshold_uncertainty_score":0.9999914,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01696064393107356,"score_gpt":0.2237987812951062,"score_spread":0.2068381373640326,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}