{"id":"W3133258115","doi":"10.2188/jea.je20200540","title":"Assessing the Relationship Between High-sensitivity C-reactive Protein and Kidney Function Employing Mendelian Randomization in the Japanese Community-based J-MICC Study","year":2021,"lang":"en","type":"article","venue":"Journal of Epidemiology","topic":"Adipokines, Inflammation, and Metabolic Diseases","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"RIKEN; Japan Society for the Promotion of Science; Ministry of Education, Culture, Sports, Science and Technology; Japan Agency for Medical Research and Development","keywords":"Mendelian randomization; Medicine; Renal function; Confidence interval; Internal medicine; Single-nucleotide polymorphism; Kidney disease; Oncology; Genetics; Gene; Genetic variants; Genotype; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaresearch"],"consensus_categories":[],"category_scores_codex":[0.01564422,0.0001229762,0.0006004981,0.0001596088,0.0003438866,0.0000263535,0.00006672958,0.00009260733,0.000007420387],"category_scores_gemma":[0.04023102,0.00006831533,0.00009619408,0.0002942814,0.0001165622,0.0002733193,0.00002116876,0.0008091436,6.175292e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005700968,"about_ca_system_score_gemma":0.000314679,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003256512,"about_ca_topic_score_gemma":0.00009109097,"domain_scores_codex":[0.9854174,0.01329688,0.0008347403,0.0001138941,0.000177496,0.0001595768],"domain_scores_gemma":[0.9836838,0.01482695,0.0007560594,0.0002718668,0.000351802,0.0001095634],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0004908185,0.0002490831,0.9947586,0.00004573615,0.000123902,0.00002982586,0.002217741,0.0003075236,0.000639258,0.0002824207,0.0001213423,0.0007337697],"study_design_scores_gemma":[0.005315207,0.0001955153,0.9845458,0.0001727779,0.000593599,0.00009617601,0.006481749,0.0001700949,0.00004441498,0.001951138,0.0003732086,0.00006031747],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9830715,0.000250395,0.006363504,0.009588927,0.0001186988,0.0005271127,0.000003593469,0.00000806588,0.00006821921],"genre_scores_gemma":[0.9967602,0.00000764661,0.0004679398,0.002280729,0.0003827146,0.00001711277,0.00005777387,0.000009805422,0.00001611186],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0245868,"threshold_uncertainty_score":0.9678535,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1282872001666278,"score_gpt":0.3878733930842037,"score_spread":0.2595861929175759,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}