{"id":"W3133358914","doi":"10.1002/hep.31755","title":"Microbiota‐Driven Activation of Intrahepatic B Cells Aggravates NASH Through Innate and Adaptive Signaling","year":2021,"lang":"en","type":"article","venue":"Hepatology","topic":"Liver Disease Diagnosis and Treatment","field":"Medicine","cited_by":204,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto General Hospital; University of Toronto; University Health Network","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; Canadian Institutes of Health Research; Canadian Liver Foundation; American Association of Immunologists","keywords":"Acquired immune system; Biology; Innate immune system; Steatohepatitis; Innate lymphoid cell; Immunology; Inflammation; Immune system; Cell biology; Cancer research; Fatty liver; Medicine; Disease; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00002574037,0.0001081007,0.0003176999,0.00003974246,0.00003391746,0.000005086821,0.00002356878,0.0000795322,0.00011405],"category_scores_gemma":[0.00002835679,0.0000944916,0.00005665247,0.0001119517,0.00008704334,0.00004843369,0.00003843329,0.00006940577,0.00001062296],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003812716,"about_ca_system_score_gemma":0.0001031962,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001483272,"about_ca_topic_score_gemma":0.00001620378,"domain_scores_codex":[0.9993153,0.00006420705,0.0001901324,0.0002211846,0.0000675734,0.0001416486],"domain_scores_gemma":[0.9994448,0.0001382124,0.00009311375,0.0001315548,0.0001400449,0.00005226963],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002065456,0.0008446723,0.3857703,0.0002828782,0.0007179243,0.0003776645,0.001765777,0.00000680039,0.605204,0.002231793,0.0004578894,0.002133664],"study_design_scores_gemma":[0.001321278,0.0002598304,0.02197334,0.0002128046,0.0003127673,0.00005185235,0.0002732916,0.0003859086,0.9741497,0.0006115743,0.0003503489,0.0000973222],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9977188,0.001045192,0.00008234441,0.0006080671,0.00006493326,0.0001863181,0.00002053054,0.00001624804,0.0002576154],"genre_scores_gemma":[0.9967281,0.0006695393,0.002099475,0.0003646705,0.00002181216,0.00001743807,0.00005893725,0.00001107482,0.00002892593],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3689456,"threshold_uncertainty_score":0.3853256,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02022258644857462,"score_gpt":0.2552798932949175,"score_spread":0.2350573068463429,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}