{"id":"W3133358914","doi":"10.1002/hep.31755","title":"Microbiota‐Driven Activation of Intrahepatic B Cells Aggravates NASH Through Innate and Adaptive Signaling","year":2021,"lang":"en","type":"article","venue":"Hepatology","topic":"Liver Disease Diagnosis and Treatment","field":"Medicine","cited_by":204,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto General Hospital; University of Toronto; University Health Network","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; Canadian Institutes of Health Research; Canadian Liver Foundation; American Association of Immunologists","keywords":"Acquired immune system; Biology; Innate immune system; Steatohepatitis; Innate lymphoid cell; Immunology; Inflammation; Immune system; Cell biology; Cancer research; Fatty liver; Medicine; Disease; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002520627,0.0006459884,0.0003482054,0.0003894787,0.0001558871,0.0002458985,0.0001572348,0.0003173508,0.001976408],"category_scores_gemma":[0.0001316551,0.0001799492,0.0002604297,0.0001216495,0.0003840423,0.0002136299,0.0003381293,0.001089285,0.0004414952],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002277782,"about_ca_system_score_gemma":0.0002399796,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002229518,"about_ca_topic_score_gemma":0.0004478782,"domain_scores_codex":[0.9997848,0.00005816195,0.00002161349,0.00003188572,0.00004470482,0.00005897936],"domain_scores_gemma":[0.9998547,0.000008799814,0.00003897987,0.00001814848,0.00001112988,0.00006828475],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001298445,0.0002415459,0.001334514,0.0001362065,0.00001677257,0.0001695803,0.00002628695,0.00006608589,0.9929453,0.0001178131,0.00009228648,0.003555149],"study_design_scores_gemma":[0.0005176345,0.006368698,0.05690522,0.00009177697,0.0001789771,0.002352491,0.0002599687,0.002239879,0.9235278,0.000531423,0.007002613,0.00002349391],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9947561,0.002376727,0.001309787,0.000226214,0.00006381525,0.00003433692,0.0001002939,0.0001007448,0.001032043],"genre_scores_gemma":[0.9959616,0.001029097,0.001201871,0.0001445361,0.0000345642,0.000059375,0.0001472893,0.00001860494,0.001403079],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001976408,"threshold_uncertainty_score":0.006611705,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02022258644857462,"score_gpt":0.2552798932949175,"score_spread":0.2350573068463429,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}