{"id":"W3133530351","doi":"10.1097/ftd.0000000000000862","title":"Quality Control of Busulfan Plasma Quantitation, Modeling, and Dosing: An Interlaboratory Proficiency Testing Program","year":2021,"lang":"en","type":"article","venue":"Therapeutic Drug Monitoring","topic":"Hematopoietic Stem Cell Transplantation","field":"Medicine","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"","keywords":"Busulfan; Dosing; Pharmacokinetics; Medicine; Therapeutic drug monitoring; Pharmacology; Bioequivalence; Medical physics; Hematopoietic stem cell transplantation; Internal medicine; Transplantation","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006364496,0.0001570848,0.0003373103,0.00007868656,0.00008945217,0.00003807643,0.00006543171,0.00006577803,0.000004459303],"category_scores_gemma":[0.0001218122,0.0001511953,0.00003784416,0.0003191645,0.00006728112,0.0001547904,0.00001066062,0.0001586016,0.000001710704],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003866393,"about_ca_system_score_gemma":0.0001991087,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005834782,"about_ca_topic_score_gemma":0.000003979936,"domain_scores_codex":[0.9984362,0.0001749699,0.0005225811,0.0003076851,0.000331574,0.0002269534],"domain_scores_gemma":[0.9986702,0.0002404699,0.0001422226,0.0002684327,0.0005638674,0.0001148596],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001773876,0.0005044549,0.4597476,0.001004456,0.0001141349,0.0000232634,0.00840362,0.0003795389,0.4409747,0.0006868043,2.559112e-7,0.08798372],"study_design_scores_gemma":[0.00746788,0.0008551772,0.3279191,0.002575804,0.0006586866,0.0001890351,0.0223144,0.2514553,0.3852297,0.0006043701,0.00003634784,0.0006941428],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9901546,0.0009117273,0.007632121,0.00009525796,0.0002714043,0.0004579532,0.00000468424,0.0001431681,0.0003291392],"genre_scores_gemma":[0.9883046,0.00003122301,0.01142425,0.00002403719,0.0001115293,0.00003838093,0.000008670977,0.00002925658,0.00002803188],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2510758,"threshold_uncertainty_score":0.6165566,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08182290215318634,"score_gpt":0.3690408574861894,"score_spread":0.2872179553330031,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}