{"id":"W3133607649","doi":"10.1093/jcag/gwab002.165","title":"A167 UNDERSTANDING THE IMPACT OF DOWNSTREAM OF KINASE 4 (DOK4) DAMAGING GENETIC VARIANTS IN THE PATHOGENESIS OF PEDIATRIC INFLAMMATORY BOWEL DISEASE (IBD).","year":2021,"lang":"en","type":"article","venue":"Journal of the Canadian Association of Gastroenterology","topic":"Helicobacter pylori-related gastroenterology studies","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"","keywords":"Inflammatory bowel disease; Pathogenesis; Immune system; Immune dysregulation; Immunology; Biology; Disease; PI3K/AKT/mTOR pathway; Signal transduction; Cancer research; Medicine; Genetics; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004938737,0.0004534301,0.0002475978,0.0006308894,0.0001784007,0.0005892633,0.0004093924,0.0007360132,0.00142532],"category_scores_gemma":[0.0005207505,0.0001968471,0.0003747806,0.0002552246,0.0002770131,0.0006900099,0.0002930927,0.0007417575,0.0002046111],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005039998,"about_ca_system_score_gemma":0.000291964,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001089629,"about_ca_topic_score_gemma":0.001187544,"domain_scores_codex":[0.9998125,0.00005644965,0.00002442079,0.0000305861,0.00003865863,0.00003737394],"domain_scores_gemma":[0.9996821,0.00009722358,0.0001107382,0.00002712755,0.0000403985,0.00004245501],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0007909992,0.0001827053,0.1477346,0.001000691,0.0002964366,0.003235,0.0002498276,0.001706264,0.7878047,0.002576713,0.001521855,0.05290021],"study_design_scores_gemma":[0.0001167146,0.001175913,0.5887532,0.000512105,0.001182849,0.02370264,0.001841707,0.009162394,0.3069744,0.005669994,0.0608431,0.00006512112],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9322557,0.05295139,0.006326781,0.003356306,0.0001159405,0.00003449099,0.000797413,0.00008171358,0.004080288],"genre_scores_gemma":[0.9741148,0.01781743,0.005594009,0.0006389932,0.00007977712,0.00002151173,0.0005675101,0.00001361705,0.001152433],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00142532,"threshold_uncertainty_score":0.004768193,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01477901150768679,"score_gpt":0.2457562085118734,"score_spread":0.2309771970041866,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}