{"id":"W3133655629","doi":"10.1093/jcag/gwab002.157","title":"A159 ANTI-TUMOR NECROSIS FACTOR THERAPY PERSISTENCE IN PATIENTS WITH PERIANAL CROHN’S DISEASE AND LUMINAL CROHN’S DISEASE: A COMPARATIVE COHORT STUDY","year":2021,"lang":"en","type":"article","venue":"Journal of the Canadian Association of Gastroenterology","topic":"Inflammatory Bowel Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"","keywords":"Medicine; Infliximab; Adalimumab; Discontinuation; Cohort; Crohn's disease; Internal medicine; Disease; Persistence (discontinuity); Tumor necrosis factor alpha; Retrospective cohort study; Concomitant; Necrosis; Gastroenterology; Surgery","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009796947,0.0003184552,0.0005056156,0.001270563,0.0007063255,0.0008444183,0.0004820535,0.0006268104,0.00222644],"category_scores_gemma":[0.002122759,0.0004915267,0.0005701448,0.001472984,0.0003920104,0.0010173,0.0007643445,0.0005251016,0.0004440501],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000513766,"about_ca_system_score_gemma":0.0005055438,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004484785,"about_ca_topic_score_gemma":0.004347095,"domain_scores_codex":[0.9992024,0.0001520452,0.0001013377,0.0002867994,0.0001080512,0.0001493803],"domain_scores_gemma":[0.998425,0.0002745447,0.0006126315,0.000183834,0.0001501125,0.0003539767],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0003570768,0.00009296057,0.998795,0.000008085537,0.00004101767,0.0001016791,0.00008146765,0.000009884137,0.0001167088,0.0000124823,0.00003159689,0.0003519889],"study_design_scores_gemma":[0.00006176058,0.0008265055,0.9975515,0.00000793236,0.00004903804,0.0005987766,0.0005078444,0.0001396078,0.0000527731,0.00001707698,0.0001800615,0.000007077878],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9995406,0.00007850647,0.00003174194,0.000007538004,0.000002896089,0.00001730321,0.0001888227,8.439624e-7,0.0001318757],"genre_scores_gemma":[0.9993359,0.00006183697,0.00006002683,0.00002325074,0.00001330408,0.00002677979,0.0003990633,0.000001122873,0.00007863252],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004484785,"threshold_uncertainty_score":0.008917332,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00802941800201096,"score_gpt":0.2163093825372474,"score_spread":0.2082799645352364,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}