{"id":"W3133663503","doi":"10.1016/j.jprot.2021.104182","title":"Protein feature analysis of heat shock induced ubiquitination sites reveals preferential modification site localization","year":2021,"lang":"en","type":"article","venue":"Journal of Proteomics","topic":"Enzyme Structure and Function","field":"Materials Science","cited_by":11,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia; Canada's Michael Smith Genome Sciences Centre","funders":"BC Cancer Agency; Canadian Institutes of Health Research; Michael Smith Health Research BC","keywords":"Ubiquitin; Proteasome; Protein folding; Cell biology; Heat shock protein; Proteostasis; Proteolysis; Heat shock; Chemistry; Cytosol; Nuclear protein; Biochemistry; Protein degradation; Biology; Enzyme","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006789697,0.0001574047,0.0001469413,0.0002862569,0.0001789576,0.0002025773,0.0001258098,0.0001777845,0.001425971],"category_scores_gemma":[0.0001120552,0.00008257673,0.0002576701,0.0002570077,0.0001030296,0.000137634,0.0001143246,0.0002474444,0.0003026876],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001664892,"about_ca_system_score_gemma":0.00008708446,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006437988,"about_ca_topic_score_gemma":0.000877641,"domain_scores_codex":[0.9999602,0.000003065798,0.000003625248,0.00001172865,0.000008984615,0.00001250967],"domain_scores_gemma":[0.9998997,0.00001406455,0.00002949863,0.000009831754,0.00001938288,0.00002749879],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001879852,0.00001074332,0.00144668,0.00001688617,0.000007111903,0.00004974518,0.000008971215,0.00002923431,0.9973457,0.00004998886,0.00002406768,0.0008228607],"study_design_scores_gemma":[0.000006230392,0.000165096,0.131416,0.000003447515,0.00003610935,0.0006144935,0.00005503992,0.001473746,0.8653283,0.00007601587,0.0008181125,0.000007411493],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9967692,0.0002944001,0.00214617,0.00002754584,0.000008456206,0.000004966631,0.0003197476,0.00002660697,0.0004028834],"genre_scores_gemma":[0.9973559,0.0001449067,0.001189639,0.00001778034,0.000003156339,0.000005571675,0.0005044883,0.000008374795,0.0007701101],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001425971,"threshold_uncertainty_score":0.004770398,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0237870233472716,"score_gpt":0.2701497247151124,"score_spread":0.2463627013678408,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}