{"id":"W3133701911","doi":"10.1093/jcag/gwab002.187","title":"A189 ELUCIDATING THE MECHANISTIC ROLE OF GLP-1R IN THE INFLAMMATORY RESPONSE OF MACROPHAGES AND B CELLS TO DIETARY FIBRES","year":2021,"lang":"en","type":"article","venue":"Journal of the Canadian Association of Gastroenterology","topic":"Digestive system and related health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Immune system; Chemokine; Dysbiosis; Inflammatory bowel disease; Inflammation; Microbiome; Receptor; Immunology; Biology; Inflammatory Bowel Diseases; Gut flora; Medicine; Internal medicine; Bioinformatics; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002435369,0.0003132229,0.0003237274,0.0002327578,0.0002097883,0.0004282527,0.000257079,0.0005912604,0.004424642],"category_scores_gemma":[0.0001330951,0.0001732029,0.0007288133,0.0001371439,0.0002456546,0.0003418058,0.0002101021,0.0008995768,0.001115555],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002244277,"about_ca_system_score_gemma":0.0002679088,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005730423,"about_ca_topic_score_gemma":0.0004486991,"domain_scores_codex":[0.9998726,0.00002469412,0.000008951714,0.00003218576,0.00002774745,0.00003379082],"domain_scores_gemma":[0.9999068,0.00001710633,0.00002766364,0.000007156823,0.0000176157,0.0000236492],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007432407,0.00005941274,0.0005992268,0.0001748154,0.00001730199,0.0001097668,0.00001598011,0.00007359438,0.9951036,0.0001095527,0.0001335155,0.002859921],"study_design_scores_gemma":[0.0003638151,0.002792889,0.06382686,0.0001575352,0.0001815371,0.001282717,0.0004310674,0.003075385,0.9095952,0.0009794151,0.01727832,0.00003530421],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9764965,0.009283073,0.007909244,0.001054486,0.0002286205,0.000080504,0.001295273,0.00009570696,0.003556438],"genre_scores_gemma":[0.9804398,0.003542064,0.008490608,0.0005842706,0.00007196167,0.0001751843,0.001149536,0.0000319744,0.005514482],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004424642,"threshold_uncertainty_score":0.01480186,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004183637475934657,"score_gpt":0.2147561411303455,"score_spread":0.2105725036544108,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}