{"id":"W3133701911","doi":"10.1093/jcag/gwab002.187","title":"A189 ELUCIDATING THE MECHANISTIC ROLE OF GLP-1R IN THE INFLAMMATORY RESPONSE OF MACROPHAGES AND B CELLS TO DIETARY FIBRES","year":2021,"lang":"en","type":"article","venue":"Journal of the Canadian Association of Gastroenterology","topic":"Digestive system and related health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Immune system; Chemokine; Dysbiosis; Inflammatory bowel disease; Inflammation; Microbiome; Receptor; Immunology; Biology; Inflammatory Bowel Diseases; Gut flora; Medicine; Internal medicine; Bioinformatics; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001638268,0.00006111686,0.0001869052,0.00006795957,0.00005634945,0.000006029605,0.0002064677,0.00009273777,0.000003867805],"category_scores_gemma":[0.0005799856,0.00003680865,0.00007807213,0.00007428828,0.00004744518,0.000003377332,0.00004346133,0.0001393501,2.029264e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008239739,"about_ca_system_score_gemma":0.0003841167,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007556191,"about_ca_topic_score_gemma":0.04280333,"domain_scores_codex":[0.9982054,0.00101153,0.0004134823,0.00006879978,0.0001430478,0.0001576947],"domain_scores_gemma":[0.9987479,0.0001159892,0.0006923973,0.0001386801,0.0002460925,0.00005891309],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.000589682,0.00003010404,0.2275325,0.00003821906,0.0001589484,0.00001018856,0.0009569288,0.0004924336,0.7691985,0.00005427649,0.0008371048,0.0001011318],"study_design_scores_gemma":[0.0008721354,0.001330827,0.885351,0.0001411126,0.00006382295,0.00009871116,0.001930726,0.00001982382,0.1088148,0.0001659242,0.001160447,0.00005071996],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9947465,0.0002133306,0.00001134916,0.004712225,0.0001361651,0.00009210942,0.00003835634,2.440653e-7,0.00004971656],"genre_scores_gemma":[0.9991683,0.00005195915,0.00006240844,0.0005886274,0.00004122502,0.000001161524,0.00000167338,0.000004870099,0.00007975486],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6603837,"threshold_uncertainty_score":0.974663,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004183637475934657,"score_gpt":0.2147561411303455,"score_spread":0.2105725036544108,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}