{"id":"W3133706563","doi":"10.30802/aalas-jaalas-20-000084","title":"A Pharmacokinetic-Pharmacodynamic Study of Intravenous Midazolam and Flumazenil in Adult New Zealand White—Californian Rabbits (<i>Oryctolagus cuniculus</i>)","year":2021,"lang":"en","type":"article","venue":"Journal of the American Association for Laboratory Animal Science","topic":"Veterinary Pharmacology and Anesthesia","field":"Veterinary","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary; Université de Montréal","funders":"Natural Sciences and Engineering Research Council of Canada; Université de Montréal","keywords":"Flumazenil; Midazolam; Medicine; Anesthesia; Righting reflex; Sedation; Pharmacokinetics; Pharmacodynamics; Saline; Benzodiazepine; Pharmacology; Reflex; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009502477,0.0005284016,0.0009751149,0.0002427533,0.0002352293,0.000389553,0.00033274,0.0004370441,0.0004401516],"category_scores_gemma":[0.001296104,0.0003748333,0.0005435466,0.0001977778,0.0008175047,0.0005558059,0.0002045291,0.0008669589,0.0002513435],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005095998,"about_ca_system_score_gemma":0.0004155665,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001417864,"about_ca_topic_score_gemma":0.001728112,"domain_scores_codex":[0.9993105,0.0001755199,0.00007039661,0.0001549381,0.0001737276,0.0001149812],"domain_scores_gemma":[0.9989957,0.0001372951,0.0003872248,0.0001330531,0.0000865499,0.0002601279],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.04514367,0.0040209,0.01160534,0.0001308773,0.0002398683,0.0002401815,0.0004148945,0.0002523214,0.9148365,0.0001105569,0.0002876691,0.02271714],"study_design_scores_gemma":[0.006339743,0.3374093,0.1910115,0.00002613779,0.000941877,0.001613795,0.0003005838,0.005038455,0.4502131,0.0001330347,0.006872774,0.00009976236],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9977956,0.0005234759,0.001125315,0.00003810819,0.00001522199,0.0001435495,0.00008413954,0.00002328563,0.0002513273],"genre_scores_gemma":[0.9957401,0.0006437462,0.002060689,0.0001132763,0.0000382155,0.0003553704,0.0003510946,0.00001385508,0.0006837325],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001417864,"threshold_uncertainty_score":0.005025446,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01480881718480479,"score_gpt":0.3134131651188732,"score_spread":0.2986043479340684,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}