{"id":"W3133768717","doi":"10.1038/s41467-021-21865-2","title":"Single cell transcriptomic analysis of murine lung development on hyperoxia-induced damage","year":2021,"lang":"en","type":"article","venue":"Nature Communications","topic":"Neonatal Respiratory Health Research","field":"Medicine","cited_by":219,"is_retracted":false,"has_abstract":true,"ca_institutions":"Children's Hospital of Eastern Ontario; Ottawa Hospital; University of Ottawa","funders":"Canadian Institutes of Health Research; Government of Canada; Deutsche Forschungsgemeinschaft; Canada Foundation for Innovation; Ontario Institute for Regenerative Medicine; University of California, San Francisco; European Respiratory Society; Lastentautien Tutkimussäätiö; Heart and Stroke Foundation of Canada; Molly Towell Perinatal Research Foundation; Ottawa Hospital Research Institute; Stem Cell Network; University of Ottawa","keywords":"Hyperoxia; Bronchopulmonary dysplasia; Lung; Stromal cell; Progenitor cell; Biology; Cell biology; Phenotype; Transcriptome; Crosstalk; Cell type; Cell; Pathology; Immunology; Medicine; Stem cell; Cancer research; Genetics; Gene; Internal medicine; Gene expression; Gestational age","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003362824,0.0001238407,0.000371826,0.0004904413,0.0001484971,0.00001149469,0.0005147618,0.0002264836,0.0001614478],"category_scores_gemma":[0.000324412,0.0001191429,0.0001492907,0.00170922,0.00006457354,0.00004231769,0.0001752616,0.001231231,0.00001915428],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002807257,"about_ca_system_score_gemma":0.0006801794,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001506936,"about_ca_topic_score_gemma":0.000620699,"domain_scores_codex":[0.9984485,0.0002071885,0.000400117,0.0002383774,0.0004702697,0.0002355267],"domain_scores_gemma":[0.9966079,0.0004027564,0.00009075874,0.002242569,0.0004636509,0.0001923793],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001705619,0.002566691,0.005444388,0.0004166138,0.001078403,0.00003982681,0.0009195521,0.00001281972,0.9700323,0.001258066,0.000607151,0.01745367],"study_design_scores_gemma":[0.001482019,0.0001822363,0.1344029,0.000136612,0.000906101,0.000005180597,0.0002392478,0.001090144,0.5689216,0.000007442763,0.2924199,0.0002065827],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9704614,0.0125474,0.00002847579,0.004751035,0.00006106299,0.0003470416,0.00003209688,0.00004466049,0.01172677],"genre_scores_gemma":[0.9909413,0.0004136051,0.006065913,0.00162685,0.00001411002,0.00003253832,0.0003295274,0.00002124507,0.0005549312],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4011106,"threshold_uncertainty_score":0.5349156,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07658983159932546,"score_gpt":0.392737073379972,"score_spread":0.3161472417806466,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}