{"id":"W3133784037","doi":"10.21203/rs.3.rs-318912/v1","title":"Sialic acid-Dependent Binding and Viral Entry of SARS-CoV-2","year":2021,"lang":"en","type":"preprint","venue":"Research Square","topic":"SARS-CoV-2 and COVID-19 Research","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"Canadian Glycomics Network; Natural Sciences and Engineering Research Council of Canada","keywords":"Sialic acid; N-Acetylneuraminic acid; Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); Virology; Coronavirus disease 2019 (COVID-19); Chemistry; Biology; Biochemistry; Medicine; Infectious disease (medical specialty); Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002079678,0.0004421095,0.0003137214,0.0002216948,0.0002774899,0.0006001773,0.0003178407,0.0003755868,0.005106951],"category_scores_gemma":[0.00047424,0.0002285971,0.0004476413,0.0002081443,0.0002592438,0.0004031269,0.0004882344,0.0004983062,0.001398754],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005608957,"about_ca_system_score_gemma":0.0003488172,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002719505,"about_ca_topic_score_gemma":0.002234488,"domain_scores_codex":[0.9997734,0.00004927986,0.0000108224,0.00002484795,0.00005459258,0.00008700315],"domain_scores_gemma":[0.9999257,0.00002515183,0.000009947111,0.0000104534,0.00001119505,0.00001753578],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001096473,0.00007084374,0.001321297,0.00008180422,0.00002528667,0.0001598329,0.00005972142,0.000671892,0.9914393,0.001627125,0.0004271838,0.003019297],"study_design_scores_gemma":[0.00008267791,0.0004116621,0.04555352,0.00002956581,0.00003243851,0.0006930067,0.0002811549,0.01190011,0.9305432,0.001529509,0.008904227,0.00003902855],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9876207,0.002688365,0.001821765,0.0002631079,0.00007294684,0.00002793762,0.0008037832,0.00002690499,0.006674403],"genre_scores_gemma":[0.9862714,0.001389542,0.001532185,0.0001382075,0.0000280281,0.00001565258,0.002493123,0.00003414334,0.008097742],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005106951,"threshold_uncertainty_score":0.01708448,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1211910368508448,"score_gpt":0.4490218929461084,"score_spread":0.3278308560952636,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}