{"id":"W3133928665","doi":"10.20944/preprints202102.0605.v1","title":"Molecular Profiles of Prostate Cancer in Men of Middle Eastern Ancestry Identifies Key Differences with Western Populations: A Multiethnic SNP Array Study","year":2021,"lang":"en","type":"preprint","venue":"Preprints.org","topic":"Prostate Cancer Treatment and Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary; University of Toronto","funders":"National Institutes of Health; Prostate Cancer Canada; National Cancer Institute; Prostate Cancer Foundation","keywords":"Prostate cancer; Biology; Cancer; Genetics; Copy-number variation; SNP; Genome; Gene duplication; Copy number analysis; SNP array; Oncology; Gene; Single-nucleotide polymorphism; Medicine; Genotype","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005749054,0.0002075525,0.0002310295,0.0004466299,0.0004175334,0.0004199639,0.0002269708,0.0003033101,0.001061576],"category_scores_gemma":[0.0009153142,0.0001759189,0.0002539239,0.0006119293,0.0001946542,0.0002640477,0.0004918545,0.0002173201,0.0002141943],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001159642,"about_ca_system_score_gemma":0.00009967468,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002230142,"about_ca_topic_score_gemma":0.002599816,"domain_scores_codex":[0.9996624,0.0001026391,0.00003005067,0.0001199715,0.00005095317,0.00003395003],"domain_scores_gemma":[0.9997298,0.00004327337,0.00007605062,0.00005967507,0.00003088794,0.00006035454],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0002808904,0.00003089336,0.9927673,0.000007703353,0.00009917792,0.0001123233,0.000296112,0.00004654772,0.003685903,0.00003251229,0.00005505929,0.002585605],"study_design_scores_gemma":[0.000004476792,0.00007455418,0.9990572,0.000001685218,0.00003772331,0.0002705572,0.0001088907,0.000100436,0.0001566162,0.00001670519,0.0001687332,0.000002498006],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9995078,0.00008131087,0.0001479894,0.000008545097,0.000001074929,0.00000415067,0.00007656141,0.000002042516,0.0001704964],"genre_scores_gemma":[0.9995796,0.00003551603,0.0001505362,0.00001264594,0.00000400343,0.000004568038,0.000105001,0.000001603237,0.0001064412],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002230142,"threshold_uncertainty_score":0.004434347,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2533420458438945,"score_gpt":0.4244769702046471,"score_spread":0.1711349243607526,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}