{"id":"W3134035549","doi":"10.1111/1751-7915.13790","title":"Revisiting a ‘simple’ fungal metabolic pathway reveals redundancy, complexity and diversity","year":2021,"lang":"en","type":"article","venue":"Microbial Biotechnology","topic":"Biofuel production and bioconversion","field":"Engineering","cited_by":37,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Office of Science; Joint Genome Institute; Nederlandse Organisatie voor Wetenschappelijk Onderzoek; Concordia University; Academy of Finland; U.S. Department of Energy","keywords":"Aspergillus niger; Metabolic pathway; Pentose phosphate pathway; Catabolism; Xylose; Biology; Pentose; Biochemistry; Metabolic engineering; Mutant; Metabolic network; Enzyme; Gene; Computational biology; Glycolysis; Fermentation","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001899699,0.0004720596,0.0003621129,0.00037469,0.0001953716,0.0009362195,0.0003185652,0.000322765,0.0005556126],"category_scores_gemma":[0.0001989123,0.0001637165,0.0003919186,0.0003848989,0.000353414,0.0009780565,0.000378772,0.0007496079,0.0003017034],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003645524,"about_ca_system_score_gemma":0.0004187829,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009520729,"about_ca_topic_score_gemma":0.00140562,"domain_scores_codex":[0.9998623,0.00001895161,0.00001311858,0.00004248948,0.00004059543,0.00002249959],"domain_scores_gemma":[0.9998705,0.00002558307,0.00002416121,0.00003382878,0.00002168321,0.00002419299],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001457482,0.00002697402,0.001508886,0.0001464752,0.00001866662,0.0003271147,0.00005245833,0.0009130869,0.9763445,0.001067211,0.00007622727,0.0193728],"study_design_scores_gemma":[0.00003932192,0.000555145,0.06005522,0.0002248329,0.0002376906,0.005626761,0.0005819725,0.02569763,0.8539181,0.01009096,0.04288461,0.00008773367],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9648778,0.005368711,0.02557162,0.0006703067,0.00005919502,0.00003076153,0.0004869164,0.0002023104,0.002732317],"genre_scores_gemma":[0.9636488,0.007923606,0.02554776,0.0002291276,0.0000296584,0.00001482133,0.001277852,0.00005039293,0.001278034],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009520729,"threshold_uncertainty_score":0.002645075,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01846592244405543,"score_gpt":0.2055350200879894,"score_spread":0.187069097643934,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}