{"id":"W3134148085","doi":"10.3389/fonc.2021.626058","title":"Pre- and Postoperative Circulating IGF-I, IGFBP-3, and IGFBP-7 Levels in Relation to Endocrine Treatment and Breast Cancer Recurrence: A Nested Case-Control Study","year":2021,"lang":"en","type":"article","venue":"Frontiers in Oncology","topic":"Growth Hormone and Insulin-like Growth Factors","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Jewish General Hospital","funders":"Skånes universitetssjukhus; Stiftelsen Konung Gustaf V:s Jubileumsfond; Fru Berta Kamprads Stiftelse; Region Skåne; Gunnar Nilssons Cancerstiftelse; Kungliga Fysiografiska Sällskapet i Lund; Medicinska Fakulteten, Lunds Universitet; Percy Falk Foundation; Percy Falks Stiftelse för Forskning Beträffande Prostata- och Bröstcancer; Lunds Universitet; Cancerfonden; Falk Foundation","keywords":"Medicine; Nested case-control study; Breast cancer; Endocrine system; Oncology; Case-control study; Internal medicine; Cancer; Hormone","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002217337,0.0002309403,0.0006891442,0.0002876127,0.00009150909,0.00002212645,0.00002733223,0.0001413035,0.00001813082],"category_scores_gemma":[0.0001903759,0.0002057926,0.00002411884,0.0003699218,0.00007856546,0.0001466378,0.00005241976,0.0002671964,4.675169e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006045892,"about_ca_system_score_gemma":0.0002991348,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00149368,"about_ca_topic_score_gemma":0.002331429,"domain_scores_codex":[0.9982864,0.0003129309,0.0004376331,0.0005420169,0.0001001206,0.000320924],"domain_scores_gemma":[0.999298,0.0001678225,0.00008531197,0.0001540313,0.0001060775,0.0001887259],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0005345941,0.0003784386,0.8914458,0.0000227362,0.0001119071,0.003067575,0.01400995,0.00002429998,0.001153556,0.00001141325,0.0001116718,0.08912808],"study_design_scores_gemma":[0.009941203,0.001998323,0.9742221,0.00008504772,0.0001573258,0.003783064,0.008025755,0.001295586,0.000075201,0.00003719377,0.0001988226,0.0001803335],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9926934,0.003087087,0.0001366649,0.002071932,0.0003181761,0.001451258,0.00007680461,0.00001708999,0.00014754],"genre_scores_gemma":[0.9976993,0.0003090936,0.001183369,0.0003999959,0.00006324585,0.0001995803,0.00001066104,0.00001833379,0.0001164734],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.08894774,"threshold_uncertainty_score":0.839198,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02209364838648254,"score_gpt":0.3230215086221118,"score_spread":0.3009278602356292,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}