{"id":"W3134171751","doi":"10.1093/jcag/gwab002.186","title":"A188 TARGETING RIPK2 TO TREAT INTESTINAL INFLAMMATION CAUSED BY SHIP DEFICIENCY","year":2021,"lang":"en","type":"article","venue":"Journal of the Canadian Association of Gastroenterology","topic":"Inflammatory Bowel Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta; University of British Columbia","funders":"","keywords":"NOD2; Inflammation; XIAP; Medicine; Cytokine; Immunology; Muramyl dipeptide; Crohn's disease; Immune system; Cancer research; Biology; Internal medicine; Apoptosis; Disease; Innate immune system; Caspase; Programmed cell death","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002002409,0.0006249466,0.0007153092,0.0002835715,0.0001910376,0.0003072972,0.0003944589,0.0005201572,0.002542214],"category_scores_gemma":[0.00009828836,0.0001805057,0.0005171265,0.0001903139,0.0003062589,0.0003529488,0.0002389961,0.00181619,0.0006980557],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002188883,"about_ca_system_score_gemma":0.0002925695,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001895719,"about_ca_topic_score_gemma":0.0003437431,"domain_scores_codex":[0.9998646,0.0000186853,0.00001994168,0.00003007691,0.00003034358,0.00003633227],"domain_scores_gemma":[0.9998997,0.000007718284,0.00002451236,0.00001104398,0.00001040324,0.00004659358],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003821862,0.001228935,0.0002967694,0.00055971,0.00009383856,0.0002893787,0.00002854331,0.0003653774,0.981985,0.0002866721,0.00121265,0.009831281],"study_design_scores_gemma":[0.002607585,0.01632791,0.006262008,0.00005808995,0.0002750595,0.001387784,0.0000859133,0.002563727,0.9536002,0.0001923459,0.01659984,0.00003955592],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9747918,0.01003215,0.005853627,0.000875604,0.0007329524,0.0005555626,0.001811353,0.0006757844,0.004671342],"genre_scores_gemma":[0.9782938,0.005241907,0.006882899,0.0004569263,0.00009915856,0.0006842684,0.002048939,0.0000520393,0.006240126],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002542214,"threshold_uncertainty_score":0.00850457,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005007836312278929,"score_gpt":0.2078525380178797,"score_spread":0.2028447017056008,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}