{"id":"W3134174432","doi":"10.1016/j.eclinm.2021.100763","title":"Adjuvant melatonin for the prevention of recurrence and mortality following lung cancer resection (AMPLCaRe): A randomized placebo controlled clinical trial","year":2021,"lang":"en","type":"article","venue":"EClinicalMedicine","topic":"Circadian rhythm and melatonin","field":"Neuroscience","cited_by":47,"is_retracted":false,"has_abstract":true,"ca_institutions":"Health Sciences Centre; Capital District Health Authority; Ottawa Regional Cancer Foundation; Ottawa Hospital; University Health Network; McMaster University; London Health Sciences Centre; St. Joseph’s Healthcare Hamilton; Surrey Memorial Hospital; Fraser Health; University of Ottawa; Canadian College of Naturopathic Medicine","funders":"Lotte and John Hecht Memorial Foundation; Gateway for Cancer Research","keywords":"Medicine; Randomized controlled trial; Adjuvant; Melatonin; Lung cancer; Resection; Placebo; Clinical trial; Surgery; Oncology; Internal medicine; General surgery; Alternative medicine; Pathology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaresearch"],"consensus_categories":[],"category_scores_codex":[0.009151154,0.0001829134,0.001594782,0.00004942572,0.0001908756,0.00002498519,0.0001553719,0.000190937,0.0000954661],"category_scores_gemma":[0.05019579,0.0001150094,0.0008649072,0.0002645276,0.0004320492,0.00009919571,0.00007412935,0.0004370006,0.000001150035],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002804564,"about_ca_system_score_gemma":0.0004125635,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003365983,"about_ca_topic_score_gemma":0.00007091269,"domain_scores_codex":[0.9950787,0.001665565,0.001877652,0.0006494251,0.0004454884,0.0002831438],"domain_scores_gemma":[0.9746541,0.02393404,0.0006886676,0.000437928,0.0001315,0.0001538115],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.973027,0.0004195835,0.004090571,0.0001346543,0.000524986,0.00003388236,0.0003515213,0.00002756678,0.002023092,0.004452037,0.0006759842,0.01423912],"study_design_scores_gemma":[0.9707027,0.0006174887,0.002360689,0.0004949624,0.001459386,0.00001181578,0.00007635707,0.01759852,0.004767815,0.0009578129,0.0007976326,0.0001548291],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9731862,0.009606245,0.004405051,0.002121245,0.005442287,0.004911754,0.00002386263,0.00003318939,0.0002701696],"genre_scores_gemma":[0.9927781,0.004054054,0.0001644957,0.000412116,0.001022118,0.0008733418,0.000006923437,0.00001745403,0.0006714422],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04104464,"threshold_uncertainty_score":0.9578048,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1067372381697417,"score_gpt":0.4486621255130911,"score_spread":0.3419248873433495,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}