{"id":"W3134174432","doi":"10.1016/j.eclinm.2021.100763","title":"Adjuvant melatonin for the prevention of recurrence and mortality following lung cancer resection (AMPLCaRe): A randomized placebo controlled clinical trial","year":2021,"lang":"en","type":"article","venue":"EClinicalMedicine","topic":"Circadian rhythm and melatonin","field":"Neuroscience","cited_by":47,"is_retracted":false,"has_abstract":true,"ca_institutions":"Health Sciences Centre; Capital District Health Authority; Ottawa Regional Cancer Foundation; Ottawa Hospital; University Health Network; McMaster University; London Health Sciences Centre; St. Joseph’s Healthcare Hamilton; Surrey Memorial Hospital; Fraser Health; University of Ottawa; Canadian College of Naturopathic Medicine","funders":"Lotte and John Hecht Memorial Foundation; Gateway for Cancer Research","keywords":"Medicine; Randomized controlled trial; Adjuvant; Melatonin; Lung cancer; Resection; Placebo; Clinical trial; Surgery; Oncology; Internal medicine; General surgery; Alternative medicine; Pathology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00206798,0.001348388,0.003045496,0.0005318606,0.0005073207,0.0009680584,0.0008208346,0.002501921,0.008290846],"category_scores_gemma":[0.002413682,0.0005189464,0.002379359,0.0004758775,0.001063592,0.000829526,0.0004839159,0.001970636,0.0006794954],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006263834,"about_ca_system_score_gemma":0.001177069,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009533569,"about_ca_topic_score_gemma":0.0021195,"domain_scores_codex":[0.9991934,0.0004532917,0.00007351894,0.0001308494,0.0000628293,0.00008625996],"domain_scores_gemma":[0.998962,0.0003335988,0.0003129024,0.00007277416,0.00007823516,0.0002403812],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9825937,0.004336239,0.0003054557,0.00159807,0.0009337376,0.00002387368,0.00002225205,0.00008963364,0.0006930609,0.00006787293,0.000484519,0.008851456],"study_design_scores_gemma":[0.9713419,0.02664262,0.0007043479,0.00009121779,0.0006102109,0.00001048837,0.00001017693,0.00009066446,0.0000727622,0.00006560409,0.0003536636,0.000006296248],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9468638,0.03184104,0.0008405824,0.001872593,0.001864178,0.01231586,0.0018828,0.000186838,0.002332425],"genre_scores_gemma":[0.9566682,0.01415098,0.002378081,0.00234067,0.001596821,0.01727634,0.001285704,0.0000235229,0.004279702],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008290846,"threshold_uncertainty_score":0.02773565,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1067372381697417,"score_gpt":0.4486621255130911,"score_spread":0.3419248873433495,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}