{"id":"W3134196763","doi":"10.1186/s12929-021-00716-8","title":"When human guanylate-binding proteins meet viral infections","year":2021,"lang":"en","type":"review","venue":"Journal of Biomedical Science","topic":"interferon and immune responses","field":"Immunology and Microbiology","cited_by":33,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"Natural Science Foundation of Fujian Province; National Natural Science Foundation of China","keywords":"Innate immune system; Biology; Intrinsic immunity; Immunity; Effector; Interferon; Pattern recognition receptor; Immune system; Immunology; Virology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.002102354,0.000281253,0.001369878,0.0009894788,0.0005579211,0.0001042494,0.001094311,0.0004784273,0.001948679],"category_scores_gemma":[0.000986198,0.0001804445,0.0006472697,0.0008205828,0.001985165,0.0002524856,0.0003463017,0.001138422,0.0001779017],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003243304,"about_ca_system_score_gemma":0.002087781,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001533478,"about_ca_topic_score_gemma":0.000002111631,"domain_scores_codex":[0.9972759,0.0004681411,0.001167848,0.0003021983,0.0002500725,0.0005358361],"domain_scores_gemma":[0.9982278,0.0001935393,0.0009312822,0.0002793079,0.0002492777,0.0001188223],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00001826954,0.0005646382,0.000002217689,0.000755456,0.0004440008,0.0001656675,0.000239713,3.547035e-8,0.08992118,0.0008830795,0.01534424,0.8916615],"study_design_scores_gemma":[0.0002729924,0.000800102,0.000002217793,0.007569528,0.0002214791,0.003002657,0.00004298711,8.272556e-8,0.001709624,0.00003588001,0.9861485,0.0001938918],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0008528146,0.9953687,0.0001596226,0.0001287709,0.002656235,0.0002037282,0.00001736818,0.00001674989,0.0005959979],"genre_scores_gemma":[0.0008989515,0.9957709,0.0001478209,0.00004215381,0.00018368,0.00001017815,0.0000224966,0.00001884878,0.002904963],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9708043,"threshold_uncertainty_score":0.9989637,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03913479376986679,"score_gpt":0.3603386994947965,"score_spread":0.3212039057249297,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}