{"id":"W3134224771","doi":"10.3389/fpain.2021.642706","title":"Pain Management in a Model of Interstitial Cystitis/Bladder Pain Syndrome by a Vaccinal Strategy","year":2021,"lang":"en","type":"article","venue":"Frontiers in Pain Research","topic":"Urinary Bladder and Prostate Research","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"Institut National de la Santé et de la Recherche Médicale; Bpifrance","keywords":"Medicine; Interstitial cystitis; Analgesic; Visceral pain; Opioid; Ovalbumin; (+)-Naloxone; Nociception; Chronic pain; Agonist; Antigen; Pharmacology; Anesthesia; Immunology; Receptor; Internal medicine; Urinary system","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.02286872,0.0002375533,0.0005932329,0.001225692,0.00008136554,0.00005763361,0.000377606,0.0002062229,0.0004947146],"category_scores_gemma":[0.001048339,0.0002441463,0.0001197256,0.001631307,0.0002394124,0.0001365761,0.0003116776,0.001321454,0.00001225349],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005047576,"about_ca_system_score_gemma":0.0006597534,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003256897,"about_ca_topic_score_gemma":0.0001576726,"domain_scores_codex":[0.9906779,0.005290556,0.0006518837,0.0007166662,0.001433684,0.001229336],"domain_scores_gemma":[0.9981384,0.0006379068,0.00004434852,0.0005909966,0.0002849407,0.0003034011],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"simulation_or_modeling","study_design_scores_codex":[0.003761078,0.003438556,0.08780559,0.004193869,0.0007048117,0.02486,0.002096175,0.001800178,0.002475093,0.0004186558,0.6050138,0.2634321],"study_design_scores_gemma":[0.01150672,0.006858593,0.0100729,0.002571824,0.00005721171,0.0002244369,0.03350883,0.9069652,0.001026861,0.01566202,0.01064726,0.0008981656],"study_design_candidate":"simulation_or_modeling","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.4819235,0.01913364,0.4345303,0.009089025,0.0005233455,0.006940555,0.0003323478,0.0001480089,0.04737933],"genre_scores_gemma":[0.978076,0.001513176,0.009194558,0.0002532059,0.00003951318,0.0002952154,0.0001912035,0.00005897975,0.01037812],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.905165,"threshold_uncertainty_score":0.9955997,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05537896323492465,"score_gpt":0.350730792830912,"score_spread":0.2953518295959874,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}