{"id":"W3134274028","doi":"10.1093/jcag/gwab002.234","title":"A236 LINACLOTIDE IS NOT DETECTABLE IN BREAST MILK OF LACTATING WOMEN: AN OPEN-LABEL, PHASE 1 STUDY","year":2021,"lang":"en","type":"article","venue":"Journal of the Canadian Association of Gastroenterology","topic":"Infant Nutrition and Health","field":"Nursing","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary; ABB (Canada)","funders":"","keywords":"Medicine; Breast milk; Dosing; Pharmacokinetics; Constipation; Lactation; Breastfeeding; Adverse effect; Internal medicine; Gastroenterology; Pregnancy; Pediatrics; Chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001302566,0.0009477102,0.002082354,0.0002403239,0.0003944983,0.0009893549,0.000671021,0.001357145,0.004452393],"category_scores_gemma":[0.001195538,0.0006068919,0.001115329,0.0003308882,0.0006981003,0.0007335802,0.0002625137,0.001914506,0.0007722007],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007810184,"about_ca_system_score_gemma":0.001330829,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006776058,"about_ca_topic_score_gemma":0.001676592,"domain_scores_codex":[0.9994757,0.000256166,0.00002214201,0.0001321379,0.00006049731,0.00005338177],"domain_scores_gemma":[0.9993303,0.000172566,0.0001950795,0.00005381047,0.0000564678,0.0001917217],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.7542944,0.05018206,0.006748634,0.002273787,0.002958962,0.0005066908,0.0003159374,0.0007167144,0.1043925,0.0001924722,0.004726835,0.07269101],"study_design_scores_gemma":[0.2901366,0.6682516,0.02098264,0.0001253414,0.00219557,0.0009010205,0.0002135669,0.001590223,0.007114162,0.0002243261,0.008197078,0.00006784423],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9907789,0.004558743,0.0005257098,0.0003623168,0.0001176972,0.001258697,0.0013648,0.0001125959,0.000920505],"genre_scores_gemma":[0.9885056,0.003081923,0.001721793,0.001202774,0.0001654625,0.001991305,0.001696823,0.00004229404,0.001591978],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004452393,"threshold_uncertainty_score":0.01489478,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02480217211770249,"score_gpt":0.3174395802546896,"score_spread":0.2926374081369871,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}