{"id":"W3134290586","doi":"10.1111/imm.13326","title":"Metabolic regulators of enigmatic inflammasomes in autoimmune diseases and crosstalk with innate immune receptors","year":2021,"lang":"en","type":"review","venue":"Immunology","topic":"Inflammasome and immune disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Institute of Infection and Immunity; Cardiff University; GlaxoSmithKline","keywords":"Inflammasome; Biology; Immune system; Crosstalk; Innate immune system; Receptor; Pattern recognition receptor; Immune receptor; Immunology; Signal transduction; Innate lymphoid cell; Acquired immune system; Inflammation; Cell biology; Genetics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002178844,0.0006308953,0.002425949,0.0003637965,0.00007931921,0.00003381964,0.0004402556,0.0006614042,0.0000558701],"category_scores_gemma":[0.0001865652,0.000523377,0.000401852,0.0004757515,0.0006787562,0.00001448815,0.0004636163,0.0003832511,0.000007031037],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002635999,"about_ca_system_score_gemma":0.000546156,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006813728,"about_ca_topic_score_gemma":0.00002454094,"domain_scores_codex":[0.9971308,0.0004297731,0.001144564,0.0006388198,0.0001384098,0.0005177077],"domain_scores_gemma":[0.9981179,0.00006038029,0.0006672762,0.0009844752,0.0001262996,0.00004367959],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001942035,0.0002720442,0.0006658126,0.005665412,0.003244504,0.00005298102,0.0003396104,0.000009173102,0.01160978,0.0007274057,0.00005615623,0.9771629],"study_design_scores_gemma":[0.001155896,0.0002953298,0.002706642,0.003263136,0.0005510581,0.000107723,0.0002086437,6.356403e-7,0.003025421,0.00002778692,0.987981,0.0006767253],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0654261,0.9335624,0.000003650958,0.00001433575,0.0002948228,0.0005282862,0.00003880171,0.0000158488,0.0001157455],"genre_scores_gemma":[0.004123534,0.9940157,0.00008575389,0.00001124994,0.0000419095,0.0001731637,0.0008404021,0.00009768976,0.0006106213],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9879249,"threshold_uncertainty_score":0.9997218,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006864807771169567,"score_gpt":0.2538182021074826,"score_spread":0.246953394336313,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}