{"id":"W3134294215","doi":"10.1016/j.biomaterials.2021.120750","title":"Stable oxime-crosslinked hyaluronan-based hydrogel as a biomimetic vitreous substitute","year":2021,"lang":"en","type":"article","venue":"Biomaterials","topic":"Retinal and Macular Surgery","field":"Medicine","cited_by":74,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; Kensington Health; University Health Network; University of New Brunswick; Toronto Western Hospital; Canada Research Chairs","funders":"Canada First Research Excellence Fund; Krembil Foundation","keywords":"Retinal; Ethylene glycol; Materials science; Biomedical engineering; Nile red; Oxime; Self-healing hydrogels; Biophysics; Chemistry; Polymer chemistry; Organic chemistry; Biochemistry; Medicine; Optics; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001983288,0.0002408823,0.0001087834,0.0001630783,0.00009369335,0.0001893329,0.000117558,0.0002274136,0.0007547498],"category_scores_gemma":[0.0001670406,0.0000935464,0.0001142777,0.0001261353,0.0001228236,0.0002838,0.000151403,0.0001844202,0.000139057],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009869861,"about_ca_system_score_gemma":0.0001672556,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001874523,"about_ca_topic_score_gemma":0.000394683,"domain_scores_codex":[0.9999346,0.0000129591,0.000006090152,0.00001122092,0.00002109051,0.00001406769],"domain_scores_gemma":[0.9999083,0.00002008549,0.00002829881,0.000007123985,0.00001506279,0.0000211444],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006710771,0.0000186911,0.00008324853,0.0000502226,0.000003853263,0.00006918501,0.00001568802,0.0001692644,0.9968336,0.000115444,0.00003399534,0.002539645],"study_design_scores_gemma":[0.000009846666,0.0001615492,0.0007477548,0.000006007127,0.00001219986,0.0001242192,0.00001224059,0.0009733017,0.9966487,0.00002546074,0.0012737,0.00000497825],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.989988,0.002471726,0.005282874,0.00007350324,0.00005832985,0.00002560916,0.0001199932,0.00004834294,0.001931653],"genre_scores_gemma":[0.9923314,0.0007832061,0.004291014,0.00004732028,0.00001068309,0.00001572347,0.00006219196,0.00001280907,0.002445586],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007547498,"threshold_uncertainty_score":0.002524853,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02079857045930569,"score_gpt":0.2791381345412421,"score_spread":0.2583395640819364,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}