{"id":"W3134301457","doi":"10.1117/12.2589729","title":"Targeted photothermal silencing of unmodified nociceptor neurons","year":2021,"lang":"en","type":"article","venue":"","topic":"Olfactory and Sensory Function Studies","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"","keywords":"Nociceptor; Gene silencing; Photothermal therapy; Neuroscience; TRPV1; Transient receptor potential channel; Chemistry; Nanotechnology; Cell biology; Nociception; Materials science; Biology; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001545765,0.0003482742,0.0003209435,0.0001101955,0.0001343258,0.0003286704,0.000361254,0.0003607317,0.0008475904],"category_scores_gemma":[0.0001247785,0.0001060237,0.0002953069,0.00008090404,0.0002689581,0.000237041,0.0002292617,0.0004867961,0.0002309399],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002559293,"about_ca_system_score_gemma":0.0001926212,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00046354,"about_ca_topic_score_gemma":0.0008924425,"domain_scores_codex":[0.9998726,0.000008159705,0.000008490383,0.00004183444,0.00003918108,0.0000297846],"domain_scores_gemma":[0.9999434,0.00001362904,0.00001542341,0.000008939235,0.00001037642,0.00000825704],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000009366285,0.000005242382,0.00001844509,0.00002316922,0.000003123496,0.00001199587,0.000006838085,0.00005652542,0.9991601,0.0000742303,0.00001123718,0.0006197157],"study_design_scores_gemma":[0.000002449016,0.00005836628,0.000414181,0.000002378132,0.000008163706,0.00004366779,0.000006717152,0.0006140522,0.9979751,0.00003773255,0.0008349983,0.000002047772],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9552403,0.002439716,0.03839618,0.0001411378,0.0001173514,0.0001273927,0.0003489411,0.0002283223,0.002960585],"genre_scores_gemma":[0.9773363,0.001710375,0.01495923,0.0001085219,0.0000194746,0.0001433732,0.0002391082,0.0000567208,0.005426943],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008475904,"threshold_uncertainty_score":0.002835453,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1384699518367551,"score_gpt":0.266698923217673,"score_spread":0.1282289713809179,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}