{"id":"W3134307717","doi":"10.1200/jco.2021.39.6_suppl.448","title":"Analysis of PFS2 by subsequent therapy in KEYNOTE-361: Pembrolizumab (pembro) plus chemotherapy (chemo) or pembro alone versus chemo as 1L therapy for advanced urothelial carcinoma (UC).","year":2021,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Bladder and Urothelial Cancer Treatments","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval; Sunnybrook Health Science Centre","funders":"","keywords":"Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.005723136,0.0007247377,0.001349201,0.0003139314,0.0001679414,0.0005608591,0.0007239615,0.0009112097,0.005337468],"category_scores_gemma":[0.00342534,0.0003275959,0.002053786,0.0003999096,0.0005228492,0.0008184076,0.0006269684,0.002118933,0.0004154666],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001400685,"about_ca_system_score_gemma":0.001452439,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004987522,"about_ca_topic_score_gemma":0.001040642,"domain_scores_codex":[0.9981413,0.001047725,0.0001337037,0.0003129239,0.0001594277,0.0002048846],"domain_scores_gemma":[0.9975106,0.001049876,0.0006823207,0.000200346,0.00006503626,0.000491886],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"observational","study_design_scores_codex":[0.9676523,0.002900559,0.005525349,0.0003569722,0.00123266,0.00003351223,0.00006676211,0.002343975,0.005646211,0.0001784874,0.000522414,0.01354082],"study_design_scores_gemma":[0.2494054,0.6604913,0.0582777,0.0001078546,0.004507429,0.0002420374,0.00009630494,0.00917352,0.01290434,0.000828705,0.003907085,0.00005834431],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9958429,0.0009899852,0.0006143285,0.0001213432,0.00004786168,0.0006393943,0.0009953784,0.00002083094,0.0007279545],"genre_scores_gemma":[0.9959635,0.0002654598,0.0008739308,0.0001151349,0.00003633923,0.0007024777,0.001084257,0.000008296904,0.000950672],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005723136,"threshold_uncertainty_score":0.03026718,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1186651903248279,"score_gpt":0.4613152924776658,"score_spread":0.3426501021528379,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}